Australian Clinical Trials

Broad Health Condition Inflammatory and Immune System
Diet and Nutrition

Specific Health ConditionAllergies
Other diet and nutrition disorders

Trial FocusPrevention

Recruitment Details

Recruitment status
Active, not recruiting

Recruitment State
VIC

Hospital

Anticipated date of first participant enrolment1/01/1990

Anticipated date of last participant enrolment1/11/1994

Phase of TrialNot Applicable

Has the study received ethics approval?Approved

Trial summary

Despite a lack of clear evidence, partially hydrolysed whey formula has been recommended at the cessation of exclusive breast-feeding in infants at high risk of developing allergic disease.  It is thought that partially hydrolysed whey formula may promote oral tolerance and prevent allergic diseases. Similarly, soy formula has previously been recommended for allergy prevention.  The primary aim of this study was to determine if the use of a partially hydrolysed formula, or a soy formula, at the cessation, or partial cessation of breastfeeding, reduced the incidence of allergic manifestations (eczema, urticaria and food reactions), in high-risk infants when compared with a conventional cows’ milk formula.

Key inclusion criteria

Family history of allergic disease (asthma, eczema, allergic rhinitis or severe food allergy)

GenderBoth males and females

Can Healthy volunteers participate? Yes

Key exclusion criteria

Nil