Clinical Trial Details

The Melbourne Atopy Cohort Study (MACS): A Randomised controlled trial of a partially hydrolysed whey and a soy formula for the prevention of allergic disease.

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Trial Information

Broad Health Condition Inflammatory and Immune System
Diet and Nutrition

Specific Health ConditionAllergies
Other diet and nutrition disorders

Trial FocusPrevention

Recruitment statusActive, not recruiting

Recruitment Details
Recruitment State
VIC

Anticipated date of first participant enrolment1/01/1990

Anticipated date of last participant enrolment1/01/1990

Phase of TrialNot Applicable

Has the study received ethics approval?Further information iconApproved

Trial summary

Despite a lack of clear evidence, partially hydrolysed whey formula has been recommended at the cessation of exclusive breast-feeding in infants at high risk of developing allergic disease.  It is thought that partially hydrolysed whey formula may promote oral tolerance and prevent allergic diseases. Similarly, soy formula has previously been recommended for allergy prevention.  The primary aim of this study was to determine if the use of a partially hydrolysed formula, or a soy formula, at the cessation, or partial cessation of breastfeeding, reduced the incidence of allergic manifestations (eczema, urticaria and food reactions), in high-risk infants when compared with a conventional cows’ milk formula.
Eligibility

Key inclusion criteria

Family history of allergic disease (asthma, eczema, allergic rhinitis or severe food allergy)

GenderBoth males and females

Can Healthy volunteers participate?Yes

Key exclusion criteria

Nil
Contact details and further information

Sponsor Primary Sponsor Type: Commercial sector/Industry
Primary Sponsor Name: Nestec Ltd,
Primary Sponsor Address: Avenue Nestle 55 CH - 180-0 Vevey
Primary Sponsor Country: Switzerland

Trial IDACTRN12609000734268

Contact person for information and recruitmentDr
Dr David Hill
Senior Consultant Allergist Murdoch Children's Research Institute The Royal Children’s Hospital Flemington Road Parkville Victoria 3052
+61 3 8344 0878

Further information icondavidjlhill@bigpond.com
Australia