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Clinical Trial Details

International Sarcoma Kindred Study: Identification of inherited risk in individuals with sarcoma

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Trial Information

Broad Health Condition Cancer
Human Genetics and Inherited Disorders

Specific Health ConditionSarcoma (also see 'Bone') - soft tissue
Other human genetics and inherited disorders

Trial Focus

Recruitment statusRecruiting

Recruitment Details
Recruitment State
NSW,QLD,SA,WA,VIC

Trial location outside Australia
United KingdomLondon
IndiaMumbai
FranceLyon
United States of AmericaUtah
Korea, Republic OfSeoul
New ZealandCanterbury

Anticipated date of first participant enrolment1/07/2009

Anticipated date of last participant enrolment1/07/2009

Phase of TrialNot Applicable

Has the study received ethics approval?Further information iconApproved

Trial summary

This study aims to identify inherited risk in individuals with sarcoma to aid in the creation of a research resource consisting of biospecimens and associated data.
Who is it for?
You may be eligible to join this study if you have been diagnosed with sarcoma. 
Study details
Participants will be identified at key sarcoma clinics, asked to complete a questionnarie and provide biospecimens (blood and tissue). The biospecimens will be stored indefinitely in a tissue bank to be utilised by researchers investigating genetic factors contributing to cancer. Information obtained from the questionnaire will be used to ascertain the family history of cancer and other factors that may contribute to development of the disease. The ongoing nature of the project will enable continual provision of important practical information for clinicians and patients leading to more favourable outcomes.
Sarcomas contribute disproportionately to cancer burden in our community, because they affect the young, treatment is costly and prolonged and morbidity and mortality is high. Genetic factors appear important in sarcomas, although they have not been well studied for the adult population. Early detection by identifying those at risk may lead to better prognoses. This project aims to create a vital research resource to enable further study into the genetic factors contributing to the hereditary risk of developing sarcoma. 
Eligibility

Key inclusion criteria

All those diagnosed with sarcoma are eligible for inclusion.  Controls must be age matched within 5 years of the proband, be older than or equal to 18 years of age, not have had a cancer diagnosis and not be a blood relative.

GenderBoth males and females

Can Healthy volunteers participate?No

Key exclusion criteria

Controls must be older than or equal to 18 years of age
Contact details and further information

Sponsor Primary Sponsor Type: Other Collaborative groups
Primary Sponsor Name: Australasian Sarcoma Study Group
Primary Sponsor Address: Peter MacCallum Cancer Centre 305 Grattan Street Melbourne Victoria 3000
Primary Sponsor Country: Australia

Trial websitewww.australiansarcomagroup.org/sarcomakindredstudy/

Trial IDACTRN12610000120077

UTNU1111-1113-4959

Contact person for information and recruitmentDr
Mandy Ballinger
The Kinghorn Cancer Centre, Garvan Institute of Medical Research, 370 Victoria Street, Darlinghurst, NSW 2010
+61 2 9355 5806
+61 2 9355 5872
Further information iconm.ballinger@garvan.org.au
Australia