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Broad Health Condition Inflammatory and Immune System
Specific Health ConditionAllergies
The Children's Hospital at Westmead - Westmead
2145 - Westmead
Anticipated date of first participant enrolment1/06/2011
Has the study received ethics approval?Approved
The project aims to test the hypothesis that the early introduction of common food allergens in the diet of infants at high risk of food allergy may increase tolerance and decrease IgE mediated allergen sensitisation and clinical food allergy. Specifically we aim to establish whether introduction of egg protein at 4 months of age into the diet of infants at high risk of atopic disease is associated with a decrease in egg sensitisation and clinical egg allergy.
Key inclusion criteria
First degree relative with atopy <4 months of age This is the age requirement for recruitment into the study- for the intervention to start at 4-6 months. Infants can be recruited from birth, but not do not start intervention until they are >4 months old.
Maximum age4 Months
GenderBoth males and females
Can Healthy volunteers participate? Yes
Key exclusion criteria
Evidence of IgE sensitization to egg at age 4 months Unable to complete study requirements Twin
Sponsor Primary Sponsor Type: Hospital
Primary Sponsor Name: Children's Hospital Westmead
Primary Sponsor Address: Hawkesbury Rd, Westmead NSW 2145
Primary Sponsor Country: Australia
Contact person for information and recruitmentProf
Professor Dianne Campbell
Department of Allergy and Immunology Childrens hospital Westmead Hawkesbury Rd, Westmead NSW 2145
Email contact firstname.lastname@example.orgAustralia