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Evaluating the effectiveness of using Peer-Dialogue Assessment (PDA) for improving pre-service teacher's perceived confidence and competence to teach physical education
Expand descriptionThe use of feedback has been shown to be important for learning. However, the feedback literature increasingly reports dissatisfaction among learners. University students are not only reporting that they do not receive feedback that is helpful for their learning but educators report the burden of giving feedback (that is often not used to improve performance). The use of Peer Dialogue Assessment (PDA) has been presented as a method of providing feedback for learners in the tertiary setting and has the potential to be a useful learning tool when used in teacher education programs. Peer Dialogue Assessment positions learners as active in seeking, generating and using feedback to improve or change their task performance. This method uses peers to initiate feedback in the form of 2-way dialogue (or discussion) after a performance and may serve to be a sustainable assessment for learning tool for use in teacher education programs. The aim of this study is to evaluate the effectiveness of using PDA for improving pre-service teacher's perceived confidence and competence to teach physical education.The following questions will be addressed: 1. What experience do undergraduate students in the BT (HPE / Primary)(Hons) programs have with assessment of teaching performance at the UoN? 2. What impact does PDA have on student's perceived competence to teach physical education? 3. What impact does PDA have on student's confidence to PE and Sport? 4. What impact does PDA have on student's self-efficacy to teach? 5. Did staff and students find the introduction of PDA in a pre-service physical education course useful as a learning tool and for improving teaching performance? It is hypothesised that confidence and competence of undergraduate students in the BT (HPE/ Primary)(Hons) will improve as a result of completing an undergraduate course with PDA embedded.
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Home assessment visits prior to discharge from hospital for patients after hip fracture: A randomised controlled trial
Expand descriptionLeaving hospital and getting back home after a hip fracture can be challenging and involve some adjustments. Participating in some form of rehabilitation has been shown to help. As part of this rehabilitation, occupational therapists are trained to assist people to overcome various problems in order to live more independent lives. They may assist with the return to home life through the development of new skills for daily living, such as household tasks and personal care. They may also make or facilitate changes to the home environment to make life easier and safer. The hospital environment can be very different to home and sometimes occupational therapists take people on a visit from hospital to their home to help to plan for discharge. These visits may have benefits such as preventing falls at home or improved ability to complete activities around the home but these home visits can be time consuming and tiring for some patients. The aim of this study is to find out if going home from hospital for a short visit with an occupational therapist prior to being discharged provides benefits for people following hip fracture compared with hospital- based discharge planning. The results will help guide health professionals to prescribe treatments to support patients to return home after a hip fracture and to make sure that these treatments are targeted to patients who will get the most benefit.
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A multicentre, randomized, controlled trial of Probiotic and Peanut Oral Immunotherapy (PPOIT) in inducing desensitisation or tolerance in children with peanut allergy compared with Oral Immunotherapy (OIT) alone and with placebo.
Expand descriptionAt present there is no cure for food allergy. People with a food allergy need to avoid the food they are allergic to in order to stay safe. However we know that accidental exposure is common. Research shows that 50% of children with a peanut allergy are accidentally exposed to peanut within 2 years. Researchers have begun to look at the effectiveness of 'oral immunotherapy' as a treatment for food allergy. In oral immunotherapy, patients with food allergy are given small amounts of the food they are allergic to and tested for food allergy after a set amount of time. Results have been mixed. Studies suggest that oral immunotherapy can induce desensitization (short term ability to tolerate the food allergen while the patient continues on therapy) but has a limited ability to induce sustained unresponsiveness (longer term ability to tolerate the food allergen after treatment is stopped for at least 2-4 weeks or longer). We previously conducted a Randomized Controlled Trial to evaluate a novel combination treatment approach involving administration of probiotic together with oral immunotherapy - Probiotic and Peanut Oral Immunotherapy (PPOIT). In our study we found that just over 80% of children who received PPOIT tolerated peanut after stopping treatment for more than 2 weeks compared with only 4% in the placebo group. PPOIT was highly effective at inducing sustained unresponsiveness - if 9 children were treated with PPOIT, 7 would benefit. PPOIT participants received a daily dose of probiotic together with peanut protein (peanut flour) for 18 months. The probiotic was taken as a fixed daily dose. The dose of peanut protein was commenced at very low levels then increased every 2 weeks over a period of 8 months to reach a maintenance dose of 2g peanut protein. This study (PPOIT-III) will build on our previous PPOIT and PPOIT-II study. PPOIT-III is a multi- site randomized controlled trial to evaluate the effectiveness of Probiotic and Peanut Oral Immunotherapy (PPOIT) in inducing desensitisation or tolerance in children with peanut allergy compared with Oral Immunotherapy (OIT) alone and with Placebo. Children will take increasing doses of peanut protein and a set amount of probiotic until a total of 18 months treatment is completed. Children will be tested for peanut allergy at the start of the study, at the end of PPOIT treatment T1 (18 months) and T2 (8 weeks) and T3 (1year) after treatment. The discovery of a safe and tolerable treatment for food allergy will have great public health benefit.
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Outpatient Terlipressin Infusion for the Treatment of Refractory Ascites.
Expand descriptionAlthough most patients with cirrhosis complicated by ascites initially respond to salt restriction and diuretics, as their liver disease progresses many lose diuretic responsiveness and develop refractory ascites, a condition for which there is no established drug treatment. Terlipressin is a synthetic analogue of vasopressin that causes splanchnic vasoconstriction, consequently improving renal blood flow and kidney function, and thus may ameliorate many of the pathophysiological changes that result in ascites formation. Its short half-life and bolus dose administration have previously precluded its long term use to treat ascites or other complications of cirrhosis. We performed a 4 week prospective trial of outpatient continuous terlipressin infusion in 5 patients with refractory ascites to examine its safety, practicality and efficacy in reducing ascites formation.
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Cerebral oxygenation and carbon dioxide in patients undergoing surgery
Expand descriptionMeasurement of actual cerebral blood flow during surgery is difficult due to the invasive or unpractical nature of the measurement tools needed. In contrast, cerebral oximetry is the continuous non-invasive measurement of cerebral oxygenation (amount of oxygen in the blood) and perfusion (the delivery of blood to the tissues of the brain). This allows anaesthetists to make critical decisions to maximise oxygen delivery and improve patient outcomes. Cerebral oximetry has been studied for more than 30 years and been commercially available for more than 2 decades. Numerous studies demonstrate that increases in blood carbon dioxide (PaCO2) increase blood flow to the brain. Carbon dioxide is a normal waste product of body metabolism, and is eliminated via the lungs. However, there are no physiological studies to date comparing the effects of normal blood carbon dioxide (normocapnia - defined as PaCO2 levels between 35-40 mmHg) and mildly elevated carbon dioxide levels (mild hypercapnia - defined as PaCO2 levels between 45-55 mmHg) on cerebral oximetry in patients undergoing major surgery. The primary aim of this study is to evaluate the effects of changes in PaCO2 on cerebral oximetry in patients undergoing major surgery. Secondary aims include the evaluation of the effects of normocapnia and mild hypercapnia on acid base blood variables, serum potassium levels, and postoperative delirium. A total of 40 subjects will be included at the Austin Hospital
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A study to investigate the relationship between stress and weight
Expand descriptionDietary restriction (dieting) is the most popular method for weight loss and is commonly the first strategy prescribed for weight loss in treating obesity. However, dietary interventions are often ineffective because energy restriction triggers the so-called “famine reaction”, a survival mechanism used by the body in order to conserve energy in times of starvation. The famine reaction involves a series of metabolic and behavioural adaptations including compensatory changes in metabolic rate, appetite and neuroendocrine hormones as well as a loss in metabolically active lean tissue in order to reduce energy requirements. Little is known about the underlying mechanisms involved in the famine reaction or whether different dietary restriction interventions can alter this response leading to more efficient and sustained weight loss. Our research group has found that a novel intermittent diet approach results in greater weight loss, reduced levels of stress hormone cortisol in blood and attenuation of the famine reaction. It is well known that dieting is psychologically stressful, and there are strong connections between stress and weight control through elevations of cortisol. Cortisol promotes central adiposity (obesity) and muscle loss and may lead to reductions in metabolic rate. Cortisol also stimulates appetite and cravings for sweet and fatty foods. For these reasons cortisol likely plays a major role in causing diet failure and resistance to weight loss. Therefore, one aspect of our study is to better understand the relationship between stress and weight loss. In order to investigate these, we firstly need to establish laboratory methods at Bond University and optimal conditions for measuring cortisol in lean healthy and obese humans. These studies will then enable us to apply these skills and perform larger weight loss interventions. The information gained for these studies will provide a greater understanding on the underlying mechanisms involved in the famine reaction and why individuals with obesity struggle to achieve weight loss goals; thereby, leading to new therapeutic strategies to target obesity.
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Effect of balance and exercise training on chemotherapy-induced peripheral neuropathy
Expand descriptionThe primary purpose of this trial is to evaluate the efficacy of an exercise and balance training intervention in patients with chemotherapy-induced peripheral neuropathy (CIPN) on functional, neurophysiological, and quality of life outcomes. Who is it for? Cancer survivors at least 3 months-post treatment, aged 18 or over, and with grade 2 or 3 CIPN. Study details All participants in this study will first complete an 8 week wait period to assess the rate of adaptive improvements occurring 'naturally' (e.g. without an exercise intervention). Participants will then complete an 8 week exercise program involving a combination of supervised and unsupervised exercise sessions, totaling three 45-60 minutes sessions per week. Sessions will include a combination of cardiovascular training, strength training and balance training. Participants will be asked to complete a number of assessments and questionnaires at enrolment, after the 8 week wait period and again after the 8 week exercise program. Assessments will include physical function tests, nerve testing, and quality of life questionnaires. This pilot study is being conducted to provide insight regarding the efficacy of exercise and balance training for the treatment of CIPN.
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Efficacy of alternative dressing and securement options for peripherally inserted central catheters (PICCs) in the prevention of PICC failure and infection. the PISCES Trial
Expand descriptionThe primary purpose of this study is to evaluate the efficacy of alternative dressing and securement devices in preventing device failure and infection in peripherally inserted central catheters (PICCs) in cancer patients. You may be eligible to participate in this trial if you are a cancer patient of any age, with a haematological malignancy or solid tumour, and are having a PICC inserted as part of your therapy (which is expected to remain in place for at least 24 hours). All participants enrolled in this trial will be randomly allocated (by chance) to receive one of four PICC dressing/securement device combinations. These combinations are the standard securement device with a simple polyurethane dressing; the standard securement device with a simple polyurethane dressing and a chlorhexidine impregnated disc; an integrated securement device and simple polyurethane dressing combined into a single device; or an integrated securement device and chlorhexidine impregnated disc. The allocated dressing will be re-applied every 7 days or more frequently if required, until 8 weeks or until the time of device removal if removal is required earlier. Participants will be asked to rate the acceptability of the device and dressing, and the device will be observed closely to examine side effects, device failures and infections. It is hoped that the findings of this trial will provide information on which PICC securement devices and dressings are most effective in preventing PICC failure and infection in cancer patients.
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Efficacy of a pre-release group-based abstinence program on extending prisoners' smoking abstinence post release from smoke-free prisons in Queensland.
Expand descriptionBackground: A smoking ban was implemented across all prisons in Queensland, Australia, in May 2014, with the aim of improving the health of prisoners and prison staff. However, post-release relapse to smoking among prisoners is common. The WISE study, conducted in the US by Clarke and colleagues (2013), is the only study that has rigorously evaluated an intervention aiming to assist individuals in remaining abstinent from smoking following release from a smoke-free prison. This intervention resulted in significantly higher abstinence rates for the intervention group compared to the control group three months post-release (11.5% and 2.4% respectively). Methods: This paper describes the design and rationale of a randomised controlled trial that aims to replicate an adapted version of the WISE intervention in Queensland prisons, with the goal of extending smoking abstinence among a population of incarcerated men due to be released from smoke-free prisons. Prisoners in the intervention group will receive four weekly sessions of a brief intervention involving group sessions of motivational interviewing and cognitive behavioural therapy, initiated in the four weeks prior to release. The control group will receive a pamphlet and brief verbal intervention at the time of baseline assessment. Assessment of post-release smoking status will be conducted by parole officers at weekly parole meetings for a maximum of three months post-release, allowing for smoking rates among the intervention and control groups to be compared. Discussion: Effective interventions that result in long-term smoking cessation are needed so as to reduce existing health disparities in this vulnerable group of Australians.
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Effect of quinoa on blood lipids and circulating adiponectin in humans.
Expand descriptionQuinoa (Chenopodium quinoa) seed is catalogued as a pseudocereal due to the similarity with the cereal family but with a different nutrient composition. Quinoa is a crop related to beetroot and spinach, grown primarily for its edible seeds. Cultivated in the Andean region between Bolivia and Peru, recent interest in this plant has been due to the nutritional value of the seeds in comparison to other cereals. Comparative to other cereals, quinoa is high in protein and rich in antioxidants (Vega-Galvez et al., 2010; Gorinstein et al., 2007). The quinoa seeds are highly nutritious and contain 60% starch and 15% protein. In addition, quinoa is a rich source of anti-oxidants including flavonoids, phenolic acids and squalene. Research has shown a potential role for quinoa in reducing oxidative stress which is increased in response to a high sugar diet (Pasko et al., 2010), and has also been reported to reduce adiposity in response to a high fat diet (Foucault et al., 2012). We have recently shown quinoa, contributing to 25% of the diet, to significantly increase adiponectin levels in C57BL/6 mouse models of obesity. Several studies have shown the benefits of increased circulating adiponectin particularly in the prevention of cardiovascular diseases, some cases of type 2 diabetes and the Metabolic Syndrome (Hotta et al., 2000; Spranger et al., 2003; Matsuzawa et al., 2004). Whilst body composition did not significantly change, a number of markers of health including lipid profiles were improved. The current study aims to assess the effect of quinoa seeds in varying quantities on adiponectin levels, blood lipid profiles and physical activity and body composition in overweight and obese humans. We hypothesise that inclusion of quinoa in the human diet will increase adiponectin levels and improve blood lipid profile in overweight and obese humans Participants receive either 25, 50, or 100 grams of quinoa per day for 12 weeks and results compared to a control group (0 grams quinoa/day).