ANZCTR search results

With an aging population and a greater number of individuals with modifiable risk factors for established chronic diseases such as arthritis, there is an urgent need for co-care management (pharmacological as well as non-pharmacological) of arthritic conditions. Patients with RA need ready access to effective self-management programs to increase patient optimize their quality of life, reduce the burden on the limited number health professionals in both Canadian and Australian health systems, especially in rural locations. A major issue in health research today is finding effective and efficient ways to exchange knowledge between researchers, health professionals and the general public, including people with arthritis. Facebook a popular social networking site which allows friends, family and business associates to connect with one another, appears to be best suited to explore as a KT strategy. Facebook has been shown to be a successful tool in recruiting and communicating with a research team, even in a multinational context. The use of Facebook as a KT medium to disseminate information from the bilingual evidence-based educational program: People Getting a Grip on Arthritis (PGrip) (Copyright) is a promising strategy to improve the health of patients with arthritis in an effective and cost-effective manner. The involvement of health professionals in patient education can allow patients with arthritis to be managed efficiently, resulting in reduced wait times for care.

This pilot study aims to determine whether the intermittent fasting approach leads to greater weight loss and greater improvements in blood sugar, cholesterol and blood pressure than a standard low energy diet in obese male war veterans. Our primary objective is to determine whether obese, male war veterans who undertake intermittent fasting (5:2 method) achieve at least 5% weight loss in six months.

This study was conducted to investigate the relationship between graded treadmill test to exhaustion and marathon time two weeks later. The aim was to see if a treadmill test could predict upcoming marathon time to help the athlete with pacing and preparation for their marathon.

To investigate the effectiveness of the adjunctive role of DHA omega-3 in outpatients with chronic anxiety and depression.

The primary purpose of the study is to assess left ventricular hypertrophy prevention at 1 year after heart transplantation with everolimus in combination with low-dose calcineurin inhibitors compared to full-dose calcineurin inhibitors.

Of the one in four young people who are diagnosed with mental disorders, only 35% seek professional help. There are many barriers preventing young people from seeking help such as: lack of recognition of mental health problems, lack of awareness about appropriate mental health services, readiness to seek help, and the stigma associated with mental illness and seeking professional health. Technological solutions have been identified as one of the key areas that should be utilised to improve treatments and access to care. Young people often seek information about health online and often prefer anonymous sources of help to traditional services. Nevertheless, despite the broad interest and vast amount of online services available to assist young people with mental health problems, evaluation is rarely conducted to determine the impact of online services on help-seeking. Focusing particularly on young adults aged 18 to 25 years, we aim to investigate the effects of a dedicated online tool to facilitate help-seeking in young adults compared to usual search strategies. All surveys and recruitment will be conducted online. Young adults will be asked to complete three surveys at baseline, one week, and one month. This project is of international relevance as one of the first dedicated online tool to facilitate help-seeking for young adults and one of the few to evaluate access to care as an outcome. It will also help inform policy and practice with evidence on whether technical solutions can increase help-seeking for young adults using a stepped-care approach.

This study aims to examine the moderating impact of baseline attentional bias on the relative efficacy of two brief interventions: mindfulness vs distraction. Participants will have their attention biases towards painful stimuli assessed and will then be randomized to receive either distraction or mindfulness before completing two experimental pain tasks.

To assess the effectiveness of butyrylated high amylose maize starch (HAMSB) in reducing gastrointestinal symptoms in volunteers suffering a functional bowel disorder. Aim 1: The primary aim is to determine if ingestion of HAMSB reduces symptoms in subjects that suffer a functional bowel disorder HAMSB. Aim 2: The secondary aim is to determine the effect of HAMSB on blood inflammatory markers and faecal microbiota in subjects suffering a functional bowel disorder.

AF is a major health and economic burden. Post-operative AF is thought to be mainly transient and reversible, however, there is very limited information about how often it may recur. Some research suggests it affects up to 8% of patients in the two years following surgery, but this is likely an under-estimate of the actual rate, as AF is often asymptomatic and there is no routine surveillance. The rationale for this study is to determine if a brief intervention increases knowledge about AF symptoms and whether a simple iPhone based handheld ECG device could be utilised to identify AF when recordings are obtained by post-operative cardiothoracic surgical patients.

This is a multi-centre (RDH and ASH), phase IV, double-blind, randomised, placebo-controlled trial of oral NTZ for the treatment of acute gastroenteritis requiring admission to hospital. Up to 300 children aged between three months and less than five years of age will be enrolled. Study participation would be from the point of enrolment until 60 days after enrolment. Enrolment will occur within 48 hours of admission to hospital. Enrolled participants will be randomised 1:1 to Nitazoxanide (NTZ) or placebo. Other treatment and management will be as per the standard of care described in the admitting hospital’s guidelines and will be ultimately the decision and responsibility of the named medical consultant. Stool samples will be collected at the point of admission. Solicitation of symptoms will be by review of routinely collected medical data recorded in the participant’s medical record, and will be supplemented by completion of study specific diary cards until discharge. All participants will be followed up at day 7 after enrolment (by telephone if already discharged) to ascertain symptoms occurring in the intervening period. At days 30 and 60 after enrolment a clinical record review will be conducted for all participants to ascertain health care attendances following discharge.