ANZCTR search results

To investigate the practice of removal of orthosis in patients with cervical trauma at time of clinical union in relation to patients perception of pain, their activity limitation and participation restriction measures

The main objective of this survey is to identify the capacity any pharmacy throughout South Australia has to be able to respond rapidly to the symptom control of palliative patients in the last few days or hours of life. This information will provide us with an objective overview as to how community pharmacies across South Australia currently are able to respond to palliative patients. It will also provide a basis to build approaches which support community pharmacy to respond to meet the needs of palliative care patient’s access to medicines. De-identified information will be used to: Guide the development of a priority medicines list for palliative patients across South Australia. This list will be chosen using three factors: clinical evidence, cost and medication accessibility. Where two or more medicines are clinically/cost equivalent we will need to identify which one has greater community accessibility. Provide feedback to the broader pharmacy community (Australian and overseas) in the form of a report published in a peer reviewed Journal; Flag factors that limit access to palliative medicines within the community to inform future quality improvement activities Create a baseline dataset from which to measure changes resulting from the implementation of quality improvement activities We would like to identify the general spread of responses of pharmacies across the state as well as differences between regions.

The exercise DVD consists of three components: warm-ups, cool-downs & stretches, and a comprehensive series of exercises designed specifically for professional orchestral musicians to target common injuries in this population. The purpose of the this trial is to evaluate: a) whether a flexible delivery of intervention will have an effect on participation and attrition levels, and b) its effect on the frequency and intensity of performance-related musculoskeletal disorders in the professional orchestral musician population. Information collected relating to changes in frequency and intensity of Performance-Related Musculoskeletal Disorders will be used to evaluate the effects of the exercise compared to a control group. Data obtained in muscle strength, flexibility, ability to manage a current performance and non-performance related musculoskeletal injury, posture, ease of movement, ability to cope with work and non-work related anxiety, energy levels, concentration will be evaluated for differences in the pre-intervention and post-intervention conditions.

A study to determine the safety, tolerability and complience tripheptanoin oil, taken as an oral supplement by patients 12 years and older, who have medical refractory epilepsy.

Interest in falls has never been stronger in both Australia and the International community. This interest is strongly fuelled by the knowledge that falls pose a serious threat to the health and wellbeing of older people and contribute to a substantial health-care burden. The primary research questions of this pilot randomised controlled study are: 1. Does physiotherapist delivered Pilates reduce falls in community-dwelling older people? 2. Does physiotherapist delivered Pilates improve standing balance in community-dwelling older people? 3. Does physiotherapist delivered Pilates improve bone mineral density in community-dwelling older people? Our hypothesis is that physiotherapist delivered Pilates will reduce falls by 30% and improve standing balance by 30% and bone mineral density by at least 1.5% in older people identified as being at high risk of falling when compared to standard care.

Insomnia and Depression share many common features such as low energy, fatigue, poor concentration and sleep difficulties. Insomnia is not just a symptom of depression however, and this is why insomnia symptoms remain nearly 50% of the time through antidepressant treatment. The objective of the current research is therefore to treat the sleep disturbances in individuals with depression and insomnia (whose symptoms have not remitted through at least 6-weeks of antidepressant treatment) with 4 sessions of CBT-I. The aims are to improve the participant's quality of sleep and reduce both their insomnia and depression severity. Our primary hypotheses are that participants receiving CBT-I will have significantly improved sleep quality and significantly reduced insomnia and depression severity compared to an information only control (IOC) group after the 8 weeks of treatment and at the 3-month follow-up session.

This study aims to allow us to gain more experience in the use of a technique called "ROLLIS" (Radiooccult lesion localisation using Iodine 125 Seeds), which was developed as an alternative to the use of hook wires to guide the operative removal of small abnormal areas in the breast that can't be felt, and has been in routine clinical use at the Mayo Clinic for ten years. Who is it for? This study expands on the inclusion criteria used for prior pilot study ACTRN12611000667910 (http://www.anzctr.org.au/trial_view.aspx?ID=342989) with addition of use of lower dose radioactive seeds (to assess whether technique is still effective) and the inclusion of lesions (a) with benign or indeterminate pathology on core biopsy and (b) use of more than one seed per participant where there are bilateral lesions and to bracket the edges of larger lesions. Trial Details The aim of the current study is to allow us to gain more experience in the use of this technique. Study participants will have both an I 1 25 seed, as well a hookwire inserted by a radiologist, to localise the abnormal area in their breast. The insertion of the seed will add approximately 5 minutes to the time usually needed by the radiologist to mark the abnormality. No extra discomfort will be experienced as local anaesthetic is routinely given for the standard procedure and no extra mammograms will be needed in most cases. The seed usually makes it quicker and easier for the surgeon to find and remove the abnormality. The seed is removed together with the abnormal area in the breast and pathology processing of the specimen occurs as per routine. The seed is removed from the specimen by the pathologist and given to the physicist for return to Medical Physics for disposal. Participants will be asked to complete two questionnaires, one at the first post op visit designed to assess their experience with the procedures, and the other will be posted to them, to evaluate how participants feel about the appearance o f their breast after the surgery. Completion of these will be voluntary. The literature suggests that cosmetic results may be improved with ROLLIS. We wish to assess participants experiences (positive or negative) with the technique and validate the use of these questionnaires for a future Randomised Controlled Trial to assess whether ROLLIS produces better patient outcomes compared with Wire Localised Surgery.

The term triage is used to refer to health services that provide a preliminary assessment of patients reporting an injury to then determine an appropriate course of management. This approach has been shown to be successful in many other elite performance domains within the athletic and dance populations. The purpose of this study is to evaluate the effectiveness of on-site physiotherapy triage clinics in a national cohort of professional orchestral musicians. Outcomes will include recording the numbers of musicians using the service, analysing the consultation information from the physiotherapists, and evaluating the 3 month follow up feedback from the musicians on their perceived helpfulness of this service.

This is a Phase 2 randomised, multi dose, double-blind study to assess the safety and efficacy of MDMA-assisted manualised psychotherapy in Australian military war veterans with chronic, treatment-resistant PTSD.

The purpose of this study is to examine the effects of fatigue on mobility, balance and falls risk in people with Multiple Sclerosis. We also would like to investigate the effect of a simple Dynamic Dorsiflexion Ankle Orthosis (DDAO) on mobility and balance.