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Phase II study of the addition of darbepoetin alfa (Aranesp) and pegfilgrastim (Neulasta) support for optimal dose-dense chemotherapy for early breast cancer
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The effects of sleep deprivation and dexamphetamine on driving, neuropsychological function and brain activity in professional drivers
Expand descriptionThis study reported on driving and vigilance after 27-h of sleep deprivation in professional drivers. The study is completed.
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A casenote audit of the efficacy of applying removable rigid dressings post transtibial amputation.
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Does tiotropium bromide lead to bronchodilation in cystic fibrosis ?
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Angiogenesis II-Safety and feasibility of autologous mesenchymal precursor cells (MPCs) in chronic myocardial ischaemia.
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Kinetic Defects in Lipoprotein Metabolism in Patients with Renal Failure
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Multicentre Randomised Controlled Trial of Laparoscopic Suture vs Mesh for Effective Repair of Large Hiatus Hernia
Expand descriptionIn a multicentre prospective double-blinded randomized trial, we will compare 3 laparoscopic methods for the repair of large hiatus hernia a) Repair using either sutures alone b) Repair with Biomesh (absorbable) c) Repair with Timesh (non-absorbable). to determine: 1) Short term and long term effectiveness of the hernia repair 2) Risk of postoperative side effects This trial will test the hypothesis that there is no difference in the incidence of recurrent hiatus hernia for the 3 different techniques of repair of large hiatus hernia. The primary outcome will be the integrity of the hiatal repair assessed by barium meal X-ray. Secondary outcomes will include clinical recurrence of the hernia, the development of post-operative reflux, the development of post-operative side effects, and overall satisfaction with the surgical outcome.
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A pilot study to examine whether an intervention that includes foot massage has any effect on the experience of nausea and vomiting following chemotherapy received by cancer patients in the ambulatory care setting.
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Nebulized fentanyl for pediatric extremity fracture
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A comparison of high flow nasal oxygen to high flow face mask oxygen in recently extubated patients.
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