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Protein turnover and energy expenditure in normal subjects, growth hormone deficiency, acromegaly and Cushing's syndrome
Expand descriptionAcromegaly, GH deficiency and Cushing's syndrome all alter body protein. The aim was to compare protein metabolism in these 3 conditions to normal subjects, along with how protein metabolism changes following surgical removal of hormone-secreting tumour.
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How is protein metabolism perturbed by long-term glucocorticoid use?
Expand descriptionLong-term glucocorticoid use causes substantial morbidity from protein loss. The aim was to determine how protein metabolism was perturbed in long-term glucocorticoid users.
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Impact of short-term low dose glucocorticoids on protein metabolism
Expand descriptionThe aim of this study is to determine if short-term low dose glucocorticoids alters protein metabolism in a way that results in protein loss. This information will help in the development of therapies that reverse or prevent protein loss in patients requiring long-term glucocorticoids.
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A Phase II trial of cellular immunotherapy on CA-125 response with M-FP cancer vaccine in patients with epithelial ovarian carcinoma
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Use of a CO2 clamp and or CPAP to stabilize respiration in patients with combined central and obstructive sleep apnoea
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Treatment of Resistant Command Hallucinations
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Open versus Laparoscopic Burch colposuspension: a randomised controlled trial.
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A Phase l Study to Determine the Pharmacokinetics of Testosterone from a Metered Dose Transdermal System (MDTS) in low libido in post-menopausal women suffering from low serum testosterome
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Bi-level Ventilatory Support during exacerbations of Cystic Fibrosis
Expand descriptionThis trial was completed recruitment in 2006 and data collection (for time-to-next readmission in 2015. Manuscript was published in the Journal of Physiotherapy 2015, vol 61:142-147.
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Virological and clinical anti-HBV efficacy of tenofovir in antiretroviral naive patients with HIV/HBV co-infection
Expand descriptionA randomised multi-centre trial of tenofovir vs lamivudine vs tenofovir/lamivudine in antiretroviral naive subjects with HIV/HBV co-infection over 48 weeks (Clinical Trial A). Plus, a 12 week viral kinetic sub-study comparing a sub-group of the patients on Clinical Trial A with a group of therapy naive HBV mono-infected subjects (Substudy A1)