ANZCTR search results

Sleep studies on 4 consecutive nights, 2 in-lab, 2 at-home, in random order

For pain relief after VATS pleurodesis, patients are given either Celebrex or Placebo for 5 days plus any other required analgesics. We aim to determine whether there is any difference in failure of the lung to adhere to the lining of the chest.

To determine whether a new form of minimally invasive ("keyhole") surgery results in less pain and suffering than traditional surgery of the lung via thoracotomy.

90 volunteers presenting for treatment at a public hospital outpatient department with restricted, painful shoulder dysfunction will be recruited. Following an initial examination to obtain baseline data subjects will be randomly allocated to one of two treatment groups: advice and exercises or advice, exercises and passive joint mobilisations. Subjects will attend between 4 and 8 treatment sessions over a one month period. Outcome measurements will then be re-assessed. Following re-assessment treatment may continue for a maximum of 10 treatment sessions over a maximum of 8 weeks. Re-assessment will be repeated 6 months after recruitment.

Oxpentifylline is being trialled as an add on drug to steroids - at present the only known med to positively influence DMD. It is thought that it may reduce some of the secondary problems in muscles such as fibrosis and inflammation.

Trial of Deflazacort, a steroid which is not currently commercially available in Australia, for boys with DMD who have failed Prednisone trials

The study will assess if treatment with Prednisolone has a positive effect in maintaining lung function in non-ambulant boys with Duchenne muscular dystrophy

To see which regimen of Prednisone - either a low daily dose or a high dose given on the two days of the weekend - gives the best positive effects (improvement in muscle strength) while minimising adverse effects (such as weight gain and behavioural changes)