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Low Dose Naltrexone in Fibromyalgia - A randomised controlled cross-over trial
Expand descriptionPreliminary evidence shows that low-dose naltrexone (LDN) has a clinically beneficial impact on fibromyalgia pain, function and quality of life. However, only a few small clinical trials with high risk of bias have investigated the effect of LDN on fibromyalgia symptoms. The primary aim of this double-blind, randomised, controlled trial is to evaluate the efficacy of LDN in reducing pain in patients with fibromyalgia over a 12-week period.
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Social Groups for Pain - A randomised controlled trial of group social education, and group facilitation of meaningful social interaction in people with chronic pain.
Expand descriptionThe primary aim of this study is to find out whether a 5-6 session, small group, education and engagement course on social interaction and meaningful activity has an effect on pain, function and social networking. There will also be a qualitative part of the study that looks at enjoyment, engagement and efficacy of the course and aims use this feedback to progressively improve the course over time. Outcome measures for the main part of the study are quantitative, based on pain and function questionnaires and there is a control group who are waitlisted for twelve weeks prior to commencement of the study. We hypothesise that there will be an increase in social connection, function and pain self-efficacy in the treatment group when compared to the control group, and that these increases will be seen at the end of the course and at 6 and 12-week follow up.