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Testing a new sleep mat, the Sonomat for use to diagnose sleep breathing problems in children with Neurodisability
The Sonomat is a non-invasive sleep mat which has recently been validated in children. The primary aim of this study is to evaluate the potential clinical application of the Sonomat, in children with Neurodisability. Participants will undergo sonomat monitoring at the same time as having their in lab sleep study (polysonomgraphy - PSG) and then use the mat at home for three nights. We hypothesise that the sonomat will be comparable to an in lan sleep study for the diagnosis of sleep disordered breathing in children with neurodisability.
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Phase 3 Efficacy and Safety Study of GTX-102 in Pediatric Subjects With AS
The primary objective of this study is to evaluate the effect of GTX-102 in cognitive function in participants with deletion-type Angelman Syndrome (AS).