ANZCTR search results

These search results are from the Australian New Zealand Clinical Trials Registry (ANZCTR).

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31330 results sorted by trial registration date.
  • Revitalising physical education, sport and physical literacy in primary schools: a quasi-randomised controlled trial

    The main objective is to determine the effectiveness of a method of assisting classroom teachers to conduct physical education and sport in primary schools. We are testing the Physical Literacy (PL) Facilitator scheme which proposes to introduce a trained PE teacher into a group of 8 schools. Roles of the Physical Literacy Facilitator include: 1) In-class professional development for the generalist classroom teacher. He or she provides teachers with new and innovative classroom teacher-friendly lesson plans, designed to be consistent with the new Physical Education National Curriculum guidelines. 2) Promote cooperation between school sport and community sport/active recreation groups by introducing children and parents to sporting groups and other clubs and physical activities, including after-school programs 3) Education of junior sport coach through local media and discussion groups. 4) Identify children with special barriers to developing sufficient physical literacy (e.g. obesity, postural problems, and motor coordination disorders) and contact parents to discuss options to overcome the barriers. 5) Encourage and facilitate engagement (and increased physical activity) in the school environment (at recesses, before and after school)

  • Efficacy of subgingival Air Polishing using Erythritol Powder in Periodontitis patients during Supportive Periodontal Therapy (SPT)

    Periodontitis is a chronic infection, which is mainly associated with Gram-negative bacteria. The aim of the systematic periodontal therapy is to reduce the number of periodontal pathogens to avoid a further progression of the disease, thus to avoid further attachment/bone loss. Systematic periodontal therapy involves, after completion of the initial hygiene phase, debridement of the exposed root surfaces by means of scaling and root planning (SRP). However, some periodontal pathogens have shown to be very resistant to the conventional treatment of periodontitis: SRP and/or surgical periodontal therapy. Even the additional use of systemic and/or local antibiotics has not been able to completely eliminate the pathogens or to maintain periodontal health over a longer period of time so far. In recent times a novel approach, the so called Air Polishing (Ap) has been developed for the removal of subgingival biolfim during SPT with the use a fine powder delivered via a commercially available injection abrasive water jet. Due to the small particle sizes of the powder the damage to the root surfaces compared to sonic, piezoelectric ultrasonic and magnetoconstrictive ultrasonics, is considerably lower. The aim of this study is to investigate whether an adjunct use of a recently introduced Erythritol Powder (Ep) could further improve the clinical and/or microbiological parameters in patients with a mild or moderate type of chronic periodontitis who already received initial therapy (SRP) but are still showing probing pocket depths (PPD) of greater than, or equal to 5mm including bleeding on probing (BOP).

  • The Stop Cancer PAIN Trial: A guideline implementation study

    This study will evaluate strategies to implement evidence-based guidelines for screening, assessment and management of cancer pain in adult outpatients presenting at oncology and palliative care services. Who is it for? You may be eligible to join this study if you are aged 18 years or above, have been diagnosed with any cancer and are attending a participating cancer centre as an outpatient. Study details All centres will start in the control arm and transition to intervention arm, but the order in which they transition will be allocated randomly (i.e. by chance). The control arm will receive screening for cancer pain with feedback to medical team to inform treatment and care according to local practice. The intervention includes the addition of strategies to implement evidence-based guidelines for screening, assessment and management of cancer pain. Strategies will include: An audit tool to enable centres to monitor how well they are implementing core standards of cancer pain assessment and management; a toolkit for identifying barriers and facilitators to practice change and implementing strategies to overcome these; QStream online health professional education to test and consolidate knowledge of cancer pain assessment and management; patient-held resources to ensure management remains centred on individual patient needs, support patient-health professional communication and coordination and help patients advocate for evidence-based, person-centred care. The study will compare a time before the strategies are introduced with the time when they are being used to see if there is a difference in the probability of a clinically important reduction in pain for patients with moderate-severe pain. It will also test the effects of the strategies on patient quality of life and empowerment, carer experience, and cost-effectiveness of care.

  • A randomised, double-blind, placebo-controlled, crossover trial investigating the effects of two nutraceutical combination formulas on mental fatigue, mood and neurocognitive performance in healthy adults.

    The primary purpose of this study is to evaluate whether acute supplementation with either of two nutraceutical combination formulas (ErgGo Mom and ErgGo POP), relative to placebo, reduces self-rated mental fatigue associated with performing cognitively demanding tasks.

  • The use of constructive worry and mindfulness body scan for helping adolescent sleep

    Previous research has shown that pre-sleep cognitive and emotional arousal increases adolescents' bedtime and sleep onset latency and decreases their total sleep time. We will test whether brief intervention can decrease pre-sleep cognitive and emotional arousal, therefore improving sleep. We hypothesis that the constructive worry and mindfulness body scan groups will lower pre-sleep arousal, and therefore improve sleep, over the no treatment group. Perfectionism may also play a role in how effective treatment is, with treatment being less effective at decreasing arousal for adolescents who score higher on a perfectionism scale, and more effective for those who score lower. Perfectionism will therefore be explored as a moderator (not an outcome measure).

  • Radiographic evaluation of the Paragon femoral stem over 2 years post hip replacement surgery

    Radiographic evaluation using RSA method to measure migration and stability of the Paragon femoral stem over 2 years post-surgery. Functional evaluation using the Oxford Hip Score. Health related quality of life evaluation using the EQ-5D questionnaire.

  • Low dose of oral corticosteroids in the treatment of painful acute otitis externa (swimmer's ear)

    Otitis externa (swimmers ear) is a frequent problem worldwide, especially in the tropics. The pain and swelling often makes proper topical treatment difficult. This study aims to evaluate the effect of oral corticosteroids (an anti-inflammatory drug) on swimmers ear.

  • TaylorActive - A Randomised Controlled Trial (RCT) investigating the effectiveness of tailored videos in promoting physical activity via the Internet.

    TaylorActive is a physical activity project for Australian adults. This project is investigating the effectiveness of tailored videos in promoting physical activity using the Internet.

  • A Study to Evaluate the Safety/Tolerability, Pharmacokinetics, and Pharmacodynamics of Oral AD-6626 in Normal, Healthy Volunteers and Subjects Heterozygous for the Aldehyde Dehydrogenase 2*1/*2 Genetic Variant With and Without Alcohol Administration

    The primary purpose of this study on healthy volunteers is to determine the safety and tolerability of oral AD-6626 without and without alcohol administration in normal healthy volunteers and subjects heterozygous (HeZ) for the aldehyde dehydrogenase 2 (ALDH2)*1/*2 genetic variant

  • Improving postoperative tonsillectomy pain management in children – a double blinded randomised control trial of a patient analgesia information sheet

    Allocation of an analgesia information sheet following tonsillectomy in children. The primary purpose of the study was to find that if allocation of an information sheet improved post operative analgesia in children and to assess if parents were more knowledgeable regarding analgesia

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