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Youth Online Wellbeing Initiative: A randomised controlled trial of online self-help Acceptance and Commitment Therapy for adolescents with anxiety
The current study aims are: 1) to determine the efficacy of ACT wherever they are to reduce anxiety and improve valued living for adolescents with anxiety; 2) to identify the level of program intensity (therapist support) required to achieve positive program outcomes; 3) to determine the mechanisms of change surrounding the intervention that are critical to program outcomes; and 4) to determine consumer acceptability, satisfaction, and geographical reach of an assisted online self-help mode of delivery. t is hypothesised that 1) adolescents who receive the ACT online program will show greater improvements in anxiety and valued than adolescents in the active control group; 2) adolescents who receive the ACT online program plus telephone support will show greater improvements in anxiety and valued living than adolescents who receive both ACT and control online self-help programs; and 3) that the mechanisms of change for the ACT conditions will be increased post intervention psychological flexibility and mindfulness.
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Effects of an exercise program for children with chronic pulmonary disease: A pilot study
Over the past 30 years, the prevalence of chronic health conditions in children and adolescents has increased dramatically. For example, the Australian National Health Survey (2004-05) reports that 12% of children between 0-15 years have asthma as a long-term health condition. Adherence to complex therapy regimes is necessary for disease management and increased quality of life. Yet, available evidence suggests that 50% or less of children with chronic health conditions are adherent to therapy. Regular exercise is considered beneficial for children with chronic health conditions; however, the impact of exercise on psychosocial health and adherence to therapy is not well understood. Furthermore, extended investigations of the literature has identified a gap in research about the benefits of exercise for children with chronic pulmonary disease other than asthma and cystic fibrosis. To date, no randomised controlled studies evaluating the effects of exercise on children with non cf bronchiectasis, broncho-pulmonary dysplasia or chronic suppurative lung disease have been conducted. The proposed study will advertise this void in the research literature by evaluating the impact of a 7 week exercise program on cardiovascular fitness, fundamental movement skills, self-esteem and quality of life. The goal of the study is to test the effects of a 7 week exercise program on cardiovascular fitness, fundamental movement skills, self-esteem and quality of life in children and adolescents with chronic pulmonary diseases like cystic fibrosis, non cf-bronchiectasis and chronic supurative lung disease (CSLD). We hypothesise that the exercise program will enhance cardiovascular fitness, fundamental movement skills (FMS), self-esteem and quality of life in those children.
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Pilot study for a new oral immunotherapy for peanut allergy
Peanut allergy affects more than 1% of the Australian population and the prevalence is increasing. To date, there is no effective treatment. This pilot study will test the safety and effectiveness in peanut allergic children of a biphasic oral immunotherapy using increasing doses of boiled peanuts followed by increasing doses of raw/roasted peanuts. Results from this pilot study will be used to design a large multi-centre randomised controlled trial.
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A Randomised Control Trial in children aged 12-23 months consuming Growing up Milk - lite or cow's milk.
Study Aims To determine if consuming Growing up milk ‘lite’ (GUMLi) compared to standard cow’s milk improves nutritional status, cognitive development and body composition profile (and health outcomes) in 1-2 year olds. Specific Objectives 1. To recruit an ethnically diverse sample of children aged prior to 1 year of age; 2. Randomise children to receive GUMLi or cow’s milk and retain children in study on intervention for 12 months from 1 year of age (+/- 4 weeks); 3. Measure anthropometry, biomarkers of macro- and micro- nutrient status, cognitive functioning, and dietary intake from 1 (+/- 4 weeks) year of age to 2 (+/- 4 weeks) years of age Study hypotheses 1. Children who consume GUMLi from age 1-2 years have a linear growth rate that is similar to children who consume cow’s milk from age 1-2 years and a % body fat increase that is less than children who consume cow’s milk from age 1-2 years. 2. Children who consume GUMLi from age 1-2 years compared to children who consume cow’s milk from age 1-2 years will be less likely to have vitamin D and iron insufficiency as defined by measurement of relevant serum biomarkers. 3. Children who consume GUMLi from age 1-2 years will have improved dietary profiles in comparison to children who consume cow’s milk from 1-2 years. 4. Children who consume GUMLi milk from age 1-2 years will have better developmental scores on the Bayley’s Scales of Infants Development in comparison to children who consume cow’s milk from 1-2 years.
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Does technology improve the compliance of daily weight monitoring in community dwelling people who have chronic heart failure.
The objective of the clinical trial is to demonstrate that monitoring of weight improves the compliance rate of CHF patient’s to self-monitor their daily weight, as well as potentially improved quality of life, enhanced management of risk factors and medication, increased cost benefits and reduced hospital readmissions.
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Randomised controlled trial of telephone based cognitive behavioural therapy (CBT) for patients with chronic lung disease and anxiety and/or depression undergoing pulmonary rehabilitation to evaluate the effect on symptoms of anxiety and depression, quality of life, and exacerbations
The aim of this study is to assess the impact and viability of CBT as a treatment for patients with chronic lung disease undergoing pulmonary rehabilitation. We expect that CBT and rehabilitation will have a synergic effect, enhancing rehabilitation benefits and improving patients’ quality of life through improved patients coping skills and psychological and physical well being
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Progressive resistance training to increase the strength of partially-paralysed muscles in people with recent spinal cord injury: a within-participant randomised controlled trial.
To compare the effectiveness of progressive resistance training and functional training versus functional training alone for increasing strength in partially-paralysed muscles in people with recent SCI. The results of this trial will have implications for the rehabilitation of people following SCI. In particular, the results will determine whether time and effort should be devoted to progressive resistance training programs or whether functional training alone will suffice.
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Telehealth for Residential Aged Care Facilities: A Pragmatic Controlled Trial
This study will examine the effectiveness of telehealth to reduce utilisation of external health services by residents in long term care. These services include visits to emergency departments, hospital admissions and visits to specialists in an ambulatory clinic settings. The model under scrutiny involves geriatrician and gerontic nurse supported comprehensive geriatric assessment and care planning, supplemented by a wide range of telehealth enabled specialist disciplines, into the residential aged care setting. It is designed to address a series of problems encountered by clinicians and administrators within Residential Aged Care Facilities (RACF) in Australia, including inadequate access to specialists; professional isolation of nurses; sub-optimal care standards; and avoidable use of hospital services in emergencies. In this introductory section, these issues are delineated and the service model designed to overcome them is described.
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Establishing a dose of exercise tolerated by stroke survivors with walking impairment: A phase 1 dose-escalation trial
Stroke survivors with poor balance and walking impairments have low activity levels and are at risk of falls. Targeted exercise can improve mobility. However, the absence of dose-finding studies may explain the limited effects of exercise delivered in many trials. In this dose-escalation study, we tested the feasibility of using dose-escalation methods, common in Phase 1 pharmaceutical trials, to determine the maximum tolerable dose of exercise in chronic stroke survivors with substantial mobility impairment.
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The determination of the satiety effect of dietary fibre using trained panelists
The effect of training on the reliability of a satiety panel has not previously been reported. The aim was to compare the effect of a training intervention in the correct use of a satiety labeled magnitude scale versus no-training on the test-retest precision and reliability of 2 hr post-prandial satiety evaluation after consumption of a standard breakfast.The training exercise will enable the selection a panel to evaluate differences in the satiety of different fibres. The primary aim of this study is to investigate if training satiety panelists in the interpretation and use of the satiety line-scale could improve the test-retest precision and reliability of satiety response to a standard breakfast meal using a parallel intervention of either (i) training or (ii) no-training. A secondary aim is to compare the postprandial glycaemia and satiety effect of a breakfast meal containing viscous fibre PGX or two non-viscous dietary fibres, inulin and wheat dextrin using the trained satiety panel from arm 1.