ANZCTR search results

These search results are from the Australian New Zealand Clinical Trials Registry (ANZCTR).

You can narrow down the results using the filters

31356 results sorted by trial registration date.
  • A Repeated Measures Reliability Study that Assesses the Consistency of the Paediatric Flatfoot Proforma in identifying the foot type of students between the ages of 7-12.

    Our study is to determine the reliability of the Paediatric Flatfoot Proforma assessment tool for differentiating pes planus sub types. We will be recruiting primary school children aged between 7-12. We will then determine whether they have a flat foot and then determine what sub type of flat foot they have. All of these measures will taken by 4th year podiatry students using an assessment tool titled the Paediatric Flat Foot Proforma.

  • Association between maternal size and total operating room time in women undergoing caesarean section: a multicentre prospective observational study

    Currently in Australia about one in five babies are delivered by Caesarean section. An increasing number of mothers having Caesarean section have increased body size. Body size is calculated from a person’s height and weight and is called BMI for body mass index. BMI is used to estimate if a person is underweight, ideal weight, overweight or obese. There is only limited information on how increased BMI affects the care for women having a Caesarean section and their babies. We plan to look at the relationship between a mother’s BMI, and how long her Caesarean section takes and whether her size is associated with complications for her or her baby after the Caesarean section. We hope this work will help plan for even better care for women having babies.

  • Games based professional learning for primary school teachers for the improvement of teaching quality and student outcomes of physical skills and self-perception during physical education.

    The aim of this study is to report the effects of a Game Centered Approach professional development program for improving Teaching quality, active learning time, fundamental movement skills, physical self perception and student perceived motivational climate. The Professional Learning for Understanding Games Education (PLUNGE) program was developed to enhance the practical PE teaching skills of primary school teachers using a Game Centered Approach in an authentic teaching environment. We hypothesized that teachers in the PLUNGE intervention, compared to those in the control group, would display higher quality teaching and greater active learning time in classes, with students displaying more favorable changes in fundamental movement skills, physical self-perception and perceived motivational climate over the study period.

  • Phase I/II clinical trial to assess the safety and biological efficacy of treatment with virus-specific, cytotoxic T-lymphocytes from partially matched third-party unrelated donors, in stem cell transplant patients with viral reactivation unresponsive to standard therapy (R3ACT trial)

    To assess the safety and efficacy of providing partially HLA matched, third party donor-derived, EBV/CMV/adenovirus-specific cytotoxic t-cells, to allogeneic stem cell/marrow transplant patients who have developed post-transplant viral infections unresponsive to standard therapy. It is hypothesised that virus-specific t-cells infusions will improve or restore the virus-specific immunity of the transplant patient in a safe manner without precipitating graft versus host disease.

  • Can a Mediterranean dietary pattern improve vascular function, cognitive health and psychological wellbeing?

    In a 6 month dietary intervention trial, we aim to investigate the effects of an Australianised Mediterranean Diet on cognitive functioning, cardiovascular health and wellbeing in an elderly Australian free-living population. We will assess memory, executive functioning, verbal fluency and speed and accuracy, psychological well-being, weight, changes in body composition, blood lipids, blood pressure, inflammatory markers, blood glucose and insulin, and vascular endothelial function. We expect to find that an Australianised Mediterranean diet will show greater improvements in these outcomes when compared to a habitual diet.

  • Post tonsillectomy pain control – a double blinded , randomised, prospective study

    This study looks at the treatment of post tonsillectomy pain. The pain experienced is severe and has a tendency to get worse five to seven days after surgery. This often has an impact on the patient’s oral intake prolonging the return to normal activity. The narcotics given for pain control are often associated with side effects. Non-steroidal anti-inflammatory drugs, such as Celecoxib (Celebrex(trademark) are superior for the control of pain minus the side effects. In this study the patient will be randomised to one of two groups and given a study pack on discharge. Both packs contain an antibiotic (Penicillin) and a “rescue” analgesic (Oxycodone - Endone(Trademark) ). One pack contains paracetamol and one contains paracetamol and Celecoxib/Celebrex. Patients will be asked to chart their recovery until their pain ceases. A data collection chart will be given to each patient on discharge. Each patient will be followed up in outpatients 5 days and 4 weeks post-surgery.

  • Short-course Isoniazid and Rifapentine for Cost-effective Latent tuberculosis Eradication

    The aim of this study is to perform a multimodal comparison of 3-month courses of weekly isoniazid and rifapentine (3HR) with 9 months of daily isoniazid (9H) for latent tuberculosis infection, using a variety of indices: a. Cost-benefit b. Patient satisfaction c. Adherence to prescribed therapy

  • A randomised controlled study investigating neurally adjusted ventilatory assist (NAVA) application during non-invasive ventilation (NIV) in Paediatrics.

    Non-invasive ventilation (NIV) as a mode of respiratory support is growing in poopularity and a number of studies have demonstrated it's benefit in both adults and children. Difficulties associated with NIV are largely attributed to leakage around the mask which adversely affects triggering and results in a time lag between patient effort and the ventilator's response. Neurally adjusted ventilatory assist (NAVA) uses an oesophageal probe which detects diaphragmatic innervation for every breath. This results in a much more timely co-ordination of ventilatory support.

  • Helping smokers to quit through increasing their appreciation of health risks information

    This study seeks to determine whether self-affirmation (boosting self-image) is effective at reducing defensiveness towards smoking risk information in smokers with and without chronic obstructive pulmonary disease. This can lead to increased acceptance of health warnings and increased quitting in smokers at high risk.

  • Study to determine levels of Fibroblast Growth Factor 23 and other associated markers of bone turnover in men with various iron store states of iron overload, iron deficiency and normal iron stores.

    This study is a cross sectional case control study which will determine levels of FGF23, a phosphate regulatory protein produced by osteocytes in men with iron overload, using haemochromatosis as a model of iron overload, in men with iron deficiency and in men with normal iron stores. Associated markers of bone metabolism will be measured in blood and urine and bone densitometry and body composition studies will be performed by Dual X-ray absorptiometry.

Tags:
  • Finding clinical trials