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Whole body vibration training in Type 2 Diabetes in a primary healthcare setting
The aim of the current study is to assess the feasibility, safety and effectiveness of a 12-wk WBV intervention on glycemic control, lipid-related cardiovascular risk factors, blood flow, body composition, balance and functional capacity among T2DM patients in a primary care context and to quantify the possible relationship between glycemic control and functional capacity, between blood flow and body composition, and between balance and physical performance among Type 2 diabetes mellitus (T2DM) participants receiving the new intervention. Sixty participants will be randomly assigned to either a whole body vibration group (WBV) or usual-care control group (CON). In addition to demographic information and clinical details, body composition (waist and hip circumference –WHR-, weight, height, percentage of body fat and fat-free mass) and blood flow (femoral artery diameter, maximum systolic velocity –VS-, maximum diastolic velocity –VD-, time averaged mean –TAM-, heart rate –HR-, pulsatility index –PI- and resistance index –RI-, mean velocity –Vmed-, peak blood velocities –TPVM- and acceleration time to peak flow –Tacel-); glycated hemoglobin -HbA1c-, fasting blood glucose, lipid-related cardiovascular risk factors (i.e. cholesterol, triglycerides, HDL, LDL, LDL/HDL and atherogenic index) and functional capacity as measured by time up and go -TUG- test, 6-minute walking test-T6MW and 30s-sit to stand-30s-STS- and measurement of center of pressure (COP) excursions in the anteroposterior (AP) and mediolateral (ML) directions, will be assessed at baseline and after the 12-week intervention. These findings may have important implications for primary healthcare-based diabetes fall prevention.
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The MitraClip System ANZ Clinical Trial is a prospective single arm clinical trial for men and women with significant, chronic mitral regurgitation to gather real-world clinical and health-economic outcome data to support the long-term safety, efficacy and economic value of the MitraClip System for treating mitral regurgitation
The primary objective of the MitraClip System ANZ Clinical Trial is to gather real-world clinical and health-economic outcome data to support the long-term safety, efficacy and economic value of the MitraClip System in the continuum of therapies for treating MR. Specifically, the following clinical and economic data will be collected: New York Heart Association (NYHA) Functional Class, Six-Minute Walk Test (6MWT) distance, quality of life (QOL) information, echocardiographic measures of left ventricular size and function, and data associated with the index hospitalization, rehospitalizations, concomitant medications and discharge facility to support the MitraClip System economic analysis.
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The effectiveness of educational interventions for medical students in reducing negative attitudes and stigmatisation toward patients with anorexia nervosa
It is frequently reported that clinicians across a range of professional disciplines experience strong negative reactions toward patients with eating disorders, particularly anorexia nervosa. The aim of the current study is to evaluate the effectiveness of two different educational interventions in reducing negative attitudes and blame-based stigma (in fourth year medicine students) toward patients with AN. The current study will compare the effectiveness of a traditional intervention (emphasising the contribution of multiple factors in the development of anorexia nervosa), a more biologically-based intervention (emphasising the biological, neurobiological and genetic factors in the development and maintenance of anorexia nervosa), and a wait-list control group (no intervention/education). Attitudes and stigma will be measured pre-intervention, immediately following the intervention, and eight weeks later.
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Red-Free Light for Measurement of Intraocular Pressure in Healthy Volunteers using Goldmann Applanation Tonometer without Fluorescein
Abstract Purpose: To evaluate the use of red free light in the measurement of intraocular pressure using a Goldmann applanation tonometer without Fluorescein. Materials and Methods: Five hundred eyes of 250 patients attending the Ophthalmology Outpatient, Suez Canal University Clinic were measured for intraocular pressure using the same Goldmann applanation tonometer mounted on Haag-Streit Slit Lamp, measurement first were done with red free light without Fluorescein then other measurements were done with cobalt blue light and topical Fluorescein on the same eyes . Results: The Mean IOP was 15.23+/- 6.3 (SD) mm Hg using the red free light without Fluorescein while the mean was 15.78 +/- 6. 7 (SD) mm Hg using cobalt blue light and after application of Fluorescein in the conjunctival sac. On paired t test analysis, this difference was not significant. Conclusion: Measurement of IOP with Goldmann appanation tonometer with red free light without the use of Fluorescein is easy, simple, save time and give an accurate IOP measurement compared to traditional measurement with cobalt blue light and topical Fluorescein.
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Influence of glycaemic index on day-long glycaemia in type 2 diabetics
It is important for people with type 2 diabetes to keep blood glucose concentrations under control. Diabetes NZ recommends choosing foods based on the Glycaemic Index A high glycaemic index food (eg: potato) is characterized as producing a fast and high blood glucose response followed by a rapid decline, whereas a low glycaemic index food (eg: pasta) induces a more gradual ascent and decline. These patterns relate to individual foods tested under laboratory conditions. Whether the same patterns of response occur in an everyday setting is unknown.
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Models of care for Acute Non-invasive Ventilation- Comparison of three tertiary Centres.
The aim is to compare three different acute non invasive ventilation services in three tertiary centres in Melbourne. All data has been collected on a password protected microsoft access database. Only a select few have the password. This study is a prospective observational study all patients received their usual care and data is de identified.
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Tai Chi for Depression
The primary purpose of the study was to determine the effects of a tai chi/qigong exercise intervention program on variables associated with mental health, quality of life, leg strength and selected metabolic parameters in participants with depression and central obesity.
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A novel device in the treatment of Obstructive Sleep Apnea and Snoring.
Royal North Shore Hospital is currently trialing a new treatment for Obstructive Sleep Apnoea and snoring. The trial is for 4 weeks, and will involve wearing the device every night. The study will assess the safety and efficacy of the device.
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Effect of long term consumption of Australian pork for weight loss and weight maintenance on cardiometabolic health, food cravings and cognition and psychological wellbeing in individuals with type 2 diabetes.
In a 6 month dietary intervention trial, we aim to compare the effects of an energy restricted low carbohydrate/high protein diet and an energy restricted high carbohydrate/low protein diet with regular moderately intense aerobic exercise on glycemic control in individuals with type 2 diabetes. Assessing weight loss and weight maintenance, cardiometabolic health (blood pressure/cholesterol/C-reactive protein/insulin/glucose), food cravings, cognitive performance, psychological wellbeing and quality of life. We believe the low carbohydrate/high protein diet will give the greatest improvements in these outcomes.
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Validating Cough Reflex Testing Against Instrumental Assessment Of Aspiration And Laryngeal Sensation.
In many patients with swallowing problems the ability to cough when food enters the lungs will be impaired. Currently there is no way to reliably identify patients who have no cough and therefore no way of protecting their airway if food/drink slips down the wrong way (aspiration). The data from this study will be used to develop a method of identifying these ‘at risk’ patients, and hence improving their management. The aim of this project is to validate a cough test against accepted measures of swallowing and sensation in the throat.