ANZCTR search results

These search results are from the Australian New Zealand Clinical Trials Registry (ANZCTR).

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32712 results sorted by trial registration date.
  • Red-Free Light for Measurement of Intraocular Pressure in Healthy Volunteers using Goldmann Applanation Tonometer without Fluorescein

    Abstract Purpose: To evaluate the use of red free light in the measurement of intraocular pressure using a Goldmann applanation tonometer without Fluorescein. Materials and Methods: Five hundred eyes of 250 patients attending the Ophthalmology Outpatient, Suez Canal University Clinic were measured for intraocular pressure using the same Goldmann applanation tonometer mounted on Haag-Streit Slit Lamp, measurement first were done with red free light without Fluorescein then other measurements were done with cobalt blue light and topical Fluorescein on the same eyes . Results: The Mean IOP was 15.23+/- 6.3 (SD) mm Hg using the red free light without Fluorescein while the mean was 15.78 +/- 6. 7 (SD) mm Hg using cobalt blue light and after application of Fluorescein in the conjunctival sac. On paired t test analysis, this difference was not significant. Conclusion: Measurement of IOP with Goldmann appanation tonometer with red free light without the use of Fluorescein is easy, simple, save time and give an accurate IOP measurement compared to traditional measurement with cobalt blue light and topical Fluorescein.

  • Influence of glycaemic index on day-long glycaemia in type 2 diabetics

    It is important for people with type 2 diabetes to keep blood glucose concentrations under control. Diabetes NZ recommends choosing foods based on the Glycaemic Index A high glycaemic index food (eg: potato) is characterized as producing a fast and high blood glucose response followed by a rapid decline, whereas a low glycaemic index food (eg: pasta) induces a more gradual ascent and decline. These patterns relate to individual foods tested under laboratory conditions. Whether the same patterns of response occur in an everyday setting is unknown.

  • Models of care for Acute Non-invasive Ventilation- Comparison of three tertiary Centres.

    The aim is to compare three different acute non invasive ventilation services in three tertiary centres in Melbourne. All data has been collected on a password protected microsoft access database. Only a select few have the password. This study is a prospective observational study all patients received their usual care and data is de identified.

  • Tai Chi for Depression

    The primary purpose of the study was to determine the effects of a tai chi/qigong exercise intervention program on variables associated with mental health, quality of life, leg strength and selected metabolic parameters in participants with depression and central obesity.

  • A novel device in the treatment of Obstructive Sleep Apnea and Snoring.

    Royal North Shore Hospital is currently trialing a new treatment for Obstructive Sleep Apnoea and snoring. The trial is for 4 weeks, and will involve wearing the device every night. The study will assess the safety and efficacy of the device.

  • Effect of long term consumption of Australian pork for weight loss and weight maintenance on cardiometabolic health, food cravings and cognition and psychological wellbeing in individuals with type 2 diabetes.

    In a 6 month dietary intervention trial, we aim to compare the effects of an energy restricted low carbohydrate/high protein diet and an energy restricted high carbohydrate/low protein diet with regular moderately intense aerobic exercise on glycemic control in individuals with type 2 diabetes. Assessing weight loss and weight maintenance, cardiometabolic health (blood pressure/cholesterol/C-reactive protein/insulin/glucose), food cravings, cognitive performance, psychological wellbeing and quality of life. We believe the low carbohydrate/high protein diet will give the greatest improvements in these outcomes.

  • Validating Cough Reflex Testing Against Instrumental Assessment Of Aspiration And Laryngeal Sensation.

    In many patients with swallowing problems the ability to cough when food enters the lungs will be impaired. Currently there is no way to reliably identify patients who have no cough and therefore no way of protecting their airway if food/drink slips down the wrong way (aspiration). The data from this study will be used to develop a method of identifying these ‘at risk’ patients, and hence improving their management. The aim of this project is to validate a cough test against accepted measures of swallowing and sensation in the throat.

  • The impact of a core medicines list on access to medicines for palliative patients within their home environment

    A recent survey of community pharmacies across South Australia (unpublished) concluded that it is difficult for community pharmacies to anticipate which medicines to stock for the treatment of symptoms commonly seen in the terminal phase of a palliative illness. This information ties in with other published qualitative studies As a result, a South Australian Palliative Care Formulary Working Party formed and subsequently developed an End of Life Essential Medicines List. This list of medicines was determined following a review of the 6 most frequently encountered symptoms noted in the terminal phase of a palliative illness - nociceptive pain, agitation, nausea/vomiting, dyspnoea, delirium and noisy breathing. The final list of medications was informed by the Working Party’s experience, the Palliative Care Therapeutic Guidelines and other locally used guidelines. The Working Party settled on these medications based on their efficacy, their usefulness in managing more than one symptom and availability on the Schedule of Pharmaceutical Benefits (PBS): - Morphine 10mg/mL Injection - Haloperidol 5mg/mL Injection - Metoclopramide 10mg/2mL Injection - Hyoscine butylbromide 20mg/mL Injection -Clonazepam 1mg Injection A hub pharmacy will be selected in the Victor Harbor Statistical Local Area (SLA): postcode: 5211 The location of the hub pharmacy will be shared with all other community pharmacies within the SLA to encourage quick access to medicines. The location of the hub pharmacy will not be shared with GPs, Nursing homes or patients and their carers. This is a quality improvement initiative. The aim of this audit is to evaluate the impact of this quality improvement strategy on: -Supporting local community clinicians to provide palliative care for non-complex patients through the standardisation of prescribing; -The viability for community pharmacies to stock medicines from an end of life essential medicines list; and -The impact of having a pharmacy hub in a SLA to support prompt and efficient supply of palliative medicines.

  • The TURN-OUT Trial: Transverse position. Using Rotation to aid Normal birth: OUTcomes following manual rotation.

    In most labours, the baby is delivered head first, face downwards. When the baby is facing sideways (Occiput Transverse) or upwards (Occiput Posterior), the labour may be more difficult, and assisted deliveries including suction cup, forceps, and caesarean section are more likely. When the mother is fully dilated, it is possible to perform an internal examination and to physically rotate the baby to the downwards (anterior) position, but it is unknown if this procedure reduces the chances of an assisted delivery. We plan to run a study looking at whether performing a procedure to turn the baby will reduce the risk of assisted delivery and caesarean section.

  • The Effect of Thermal Stimuli on the Response to Intradermal Capsaicin in Healthy Male Participants

    We wish to investigate the effect of two different types of thermal stimuli on the responses (spontaneous pain, flare, allodynia and hyperalgesia) to intradermal capsaicin in healthy male volunteers.

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