ANZCTR search results

The primary prupose of this study is to determine the effect of the implementation of an exercise program in post-surgical LapBand patients, in regards to weight loss

The aim of this psychological assessment study is to identify baseline psychological correlates which may help predict individuals who are unlikely to achieve minimal weight loss goals. Successful screening and identification of individuals who are unlikely to achieve minimal weight loss goals could potentially reduce patient distress and such individuals could be directed to more suitable weight loss approach. It is also important to understand factors which may inhibit or reduce weight loss in those individuals in order to maximise weight loss outcomes. The aim is to investigate how specific traits affect weight loss outcomes and identify those areas which through the use of behaviour therapy, can be modified to improve weight loss outcomes.

This study aims to examine the effectiveness of the Genutrain knee brace in people with symptomatic osteoarthritis of the knee. The Genutrain knee brace will be compared with a standard generic (commerically available) neoprene knee brace and outcomes based on pain and activity will be assessed. It is hypothesised that the Genutrain knee brace will provide greater pain relief and allow improved movement of the knee joint when compared with a standard knee brace.

Anaphylaxis is a severe potentially life-threatening allergic reaction. The accepted management is intramuscular adrenaline. With intravenous adrenaline being a last resort therapy. The investigators believe that intravenous adrenaline given slowly as a dilute infusion is a better therapy, with more rapid onset (especially in patients with low blood pressure) with a similar side-effect profile to intramuscular adrenaline. This study is part of a wider PhD assessing this hypothesis and also the pharmacological behaviour of adrenaline.

The PREVAIL (Trademark) Single Port Access Paragastric Implant System is a novel approach to the treatment of morbid obesity. The saline-filled Paragastric Implant is placed in a minimally invasive fashion into the abdominal cavity in the space adjacent the stomach, thereby reducing the ability of the stomach to expand and reducing oral intake. The Paragastric Implant volume can be adjusted by the addition or removal of sterile saline through a subcutaneous port. This trial is a single-arm, prospective, multi-center study designed to demonstrate the safety and effectiveness of the Vibrynt PREVAIL (Trademark) Paragastric Implant System in the treatment of morbid obesity. The primary end point of this study will be the six-month efficacy rate, as measured by the average percent excess weight loss for subjects treated with the PREVAIL(Trademark) Single Port Access Paragastric Implant System . Subjects will be followed for three years for long term safety and efficacy evaluations.

The primary purpose of this study is to compare best practice medical management versus placement of the Lap-Band System, mostly in terms of weight loss.

Objectives: The overarching objective of this proposal is to develop and assess the efficacy of a unique online psychological intervention that is accessible, user friendly and engaging to men with CaP and that reduces the stigma of psychological distress in the context of prostate cancer. Aims: This project will be conducted over three phases. Phase 1: Development of resources - Develop an online assessment template to assess the psychological status of men with prostate cancer and to highlight specific areas of distress to the patient and the researchers. - Develop a 6 module self-directed online CBT-based psychological intervention for men with CaP. Phase 2: Consumer evaluation of developed resources - Assess the usability and acceptability of the online program with a consumer population Phase 3: Randomised controlled trial examining the efficacy of the online intervention - Assess the efficacy of the online intervention as compared to a usual care group across a number of domains including: Mental Health -Anxiety, Depression, Stress (DASS); Marital Satisfaction; Prostate-Specific Quality of Life (QoL) 1. Urinary control; 2. Sexual intimacy; 3. Sexual confidence; 4. Spouse affection 5. Masculine self-esteem; 6. Health worry; 7. PSA concern; 8. Cancer control; 9. Informed decision; 10. Regret; and, 11. Positive outlook.

The Cancer Council NSW has implemented the Eat It To Beat It Program designed to decrease cancer risk, with the focus on changing individual food purchasing decisions to increase fruit and vegetable consumption. Strategies target parents and carers of primary school aged children in the Hunter region of NSW. The goals of this nutrition intervention program are to increase the consumption of fruit and vegetables by the target group by 0.4 serves per day by the end of 2010. The Eat It To Beat It Program has a number of strategies to achieve its aims. One of the strategies for the program is The Fruit & Veg $ense Program. This program consists of: * The Shopping and Budgeting session. * Two newsletters sent to participants at weeks 2 and 5. The randomised controlled trial will determine the efficacy of the Fruit & Veg $ense Program. The research hypothesis is that “Compared with the control group, the participants who complete the Fruit & Veg $ense Program will consume more fruit and vegetables.”

Knee osteoarthritis (OA) is a progressive degenerative condition of articular cartilage and subchondral bone that leads to significant physical and psychological disability, and adversely affects daily function and quality of life. Current treatment of knee OA is associated with limitations and side effects that restrict their ability to effectively treat the symptoms of the condition and stop its progression. Recent research has demonstrated that Human adipose-derived stem cells (ADSCs) are safe for use in Humans and can differentiate into cartilage and bone, suggesting a potential treatment in osteoarthritis. This study aims to assess the changes in pain, cartilage and bone appearance, activity levels and lower extremity functional ability of patients with knee OA following intra-articular ADSC injection compared to usual treatment of Hylan G-F 20 (Synvisc [Registered Trademark]).

This study is been carried out to investigate the variation in size of the lacrimal punctum in a normal adult population. The lacrimal punctaare are the openings on the inner aspect of your eye which drains tears from the eye into the nose. This opening is important for correct drainage of tears and abnormalities in its size can lead to problems such as watery eye, or dry eye disease.