ANZCTR search results

This study looks at the impact of physical activity on fatigue and quality of life in people with thoracic lung cancer. Who is it for? You may be eligible to join this study if you have invasive thoracic cancer which is not suitable for surgical removal. Trial details: Participants will be divided into two groups. One group (the control group) will receive standard care for 6 months. The other group will take part in a physical activity program, with behavioural support for 8 weeks in addition to standard care. Study aims: To compare self-reported fatigue levels and quality of life in the two groups to determine the effects of exercise.

This study investigates the efficacy of physiotherapy treament for recovery of arm movement following severe stroke. The hypothesis is that physiotherapy treatment with the Bobath Concept will be more effective in improving arm movement than a placebo treatment.

The primary purpose of this study is to determine whether the differences in the product characteristics of 2 commercially available hyaluronic acid (HA)-based dermal fillers translate to differences in their long term durability in patients with severe age-related nasolabial folds (NLFs), following a single administration.

There is little evidence base to direct physicians as to when to use paracetamol for the management of pain in palliative patients who require opioids. In particular, it is not known whether the addition of eight large paracetamol tablets (4gm) to the daily medications of patients, using low-dose strong opioids, improves pain control or merely adds to patients’ tablet burden. This study is a double-blind randomised controlled trial, designed to investigate any analgesic benefits of paracetamol for patients using low-dose strong opioids. It requires patients to take either 4gm of paracetamol or placebo in addition to their usual daily opioids for five days and then to swap to placebo or 4gm of paracetamol for the next five days. Patients are asked to complete a daily diary throughout the ten day study period that records subjective and objective measures of pain control, aspects of common opioid side effects and quality of life. These records will be quantitatively analysed for statistical significance using paired t-test.

A randomised controlled trial will be conducted of 1650 patients seeking care for recent onset low back pain. The trial will assess the effect that paracetamol has on the recovery from low back pain. Specifically, it will determine whether paracetamol shortens days to recovery from low back pain compared to placebo, and whether taking a ‘regular dosing’ of paracetamol is more effective than taking an ‘as required’ dosing. The trial will also measure the effect of paracetamol on disability, function, sleep quality and determine the cost-effectiveness of paracetamol for managing patients with low back pain.

The aim of the study is to see if the single sterile water injection technique is as effective as the standard four injection technique in relieving lower back pain during labour and birth. If the difference in pain relief between the two techniques, thirty minutes after injection(s) is no greater or less than 1 centremeter on the VAS, the trial will have proven it's hypothesis

The intended purpose of this study is to objectively quantify the improvements in pain and function experienced by patients after having partial knee replacement surgery to the patella of their knees.

The purpose of this study is to compare two surgical approaches to see which has the best muscle healing post-operatively.

The purpose of this study is to compare two differnt types of prosthesis used in total knee replacement to see which gives the best functional outcome.

Agoraphobia, a quite common anxiety disorder in Australia, is defined as the fear of being in places or situations from which escape might be difficult or embarrassing. Standard exposure therapy is not bereft of weaknesses. Hence, new research lines study the virtual reality exposure therapy. Virtual reality allows patients to interact in real time 3D computerized worlds. The project will include a sample of volunteered patients suffering from agoraphobia who will be exposed to virtual environments specifically created for the present study using an affordable game editor. This collaborative effort’s goal is finally to search for a better understanding of agoraphobia innovative treatment and to discover presence objective measure instruments.