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For pain relief after VATS pleurodesis, patients are given either Celebrex or Placebo for 5 days plus any other required analgesics. We aim to determine whether there is any difference in failure of the lung to adhere to the lining of the chest.

To determine whether a new form of minimally invasive ("keyhole") surgery results in less pain and suffering than traditional surgery of the lung via thoracotomy.

90 volunteers presenting for treatment at a public hospital outpatient department with restricted, painful shoulder dysfunction will be recruited. Following an initial examination to obtain baseline data subjects will be randomly allocated to one of two treatment groups: advice and exercises or advice, exercises and passive joint mobilisations. Subjects will attend between 4 and 8 treatment sessions over a one month period. Outcome measurements will then be re-assessed. Following re-assessment treatment may continue for a maximum of 10 treatment sessions over a maximum of 8 weeks. Re-assessment will be repeated 6 months after recruitment.

Oxpentifylline is being trialled as an add on drug to steroids - at present the only known med to positively influence DMD. It is thought that it may reduce some of the secondary problems in muscles such as fibrosis and inflammation.

Trial of Deflazacort, a steroid which is not currently commercially available in Australia, for boys with DMD who have failed Prednisone trials

The study will assess if treatment with Prednisolone has a positive effect in maintaining lung function in non-ambulant boys with Duchenne muscular dystrophy

To see which regimen of Prednisone - either a low daily dose or a high dose given on the two days of the weekend - gives the best positive effects (improvement in muscle strength) while minimising adverse effects (such as weight gain and behavioural changes)

Sucrose when given to newborn infants has analgesic properties, especially when used for the relief of procedural pain. The calming effects of the sweet taste, cause the release of naturally occuring endorphins (morphine- like substances). The aim of this study is to show that sucrose has the same pain relieving effects in the infant of a substance dependent mother, compared to healthy (matched) infant.

It has been found that if lymphoma recurs after transplantation it often does so in sites involved prior to transplantation. Radiotherapy can prevent some of these relapses, and may improve the overall results of transplantation. Radiotherapy is often given only to bulky sites (i.e more than 5-10 cm in size) of lymphoma following transplantation, but the optimal dose and area of radiotherapy is not known. It is possible that treating all the areas of lymphoma (including non-bulky areas) may be more effective. In this research study, radiotherapy will be given to all the areas known to be affected by lymphoma (other than bone marrow). The aims of this study are to: (1) assess the ability of radiotherapy to reduce the risk of relapse following transplantation, and (2) carefully evaluate the side effects of adding radiotherapy to transplantation.