ANZCTR search results

The Promoting Early Communication workshop provides parents with information and strategies, to support their child's language development during everyday activities. An online version of the Promoting Early Communication workshop has been developed as an option for parents who find it difficult to attend a face-to-face workshop in person, or those who would prefer an online version. The aims of this research are to find out whether: • parents who use the online Promoting Early Communication workshop, find it as useful as parents who attend the face-to-face Promoting Early Communication workshop. • online service delivery has comparable costs with those of a face-to-face workshop • parent engagement with online service delivery is comparable with parent engagement with face-to-face workshops. We hypothesise that that parents who complete the online workshop will find it as useful as parents who participate in the face-to-face workshop. It is also hypothesised that provision of the online parent education package will prove to be a cost effective service delivery option that also has additional non-financial operational benefits for the service. It is hypothesised that parent engagement with the online parent education package will be equivalent to or better than engagement with face-to-face workshops.

To evaluate whether an interdisciplinary bronchiectasis clinic will be acceptable to patients in a regional area.

The purpose of this study is to collect and analyse how lung cancer is managed in Australia, and examine patient outcomes. Who is it for? You may be eligible to join this study if you are aged 18 years or above and have been diagnosed with lung cancer. Study details: Participants in this study will continue to receive routine clinical care, which will not be impacted by involvement in this study. All enrolled patients will have clinical data collected for up to 5 years. Data captured will include presentation of the disease, surgical interventions, prescription of system therapies, and information regarding multidisciplinary management and outcomes of lung cancer in the routine clinical practice setting. This registry will be used to help to describe the current practice patterns so that we can continue to improve the health outcomes of patients diagnosed with lung cancer in Australia.

We will recruit 60 people with stroke from 1-month post-hospital discharge to an exploratory study of patient responses to a novel virtual reality immersive experience. This VR experience is designed to compare stroke survivors’ responses to single- versus multi-patient room types according to 4 main factors i.e. social connectivity, access to nature/ greenery via window view, noise, and room size/expanse. We will gauge people’s responses using preference and emotional ratings. We will also track stroke survivors’ physical responses using a pulse probe and a wearable motion sensor. Following the 1 hour VR experience we will gather further insights into how people think and feel about patient room design. This study will run for 2 years. On conclusion of this study, we plan to be able to show the feasibility of a VR environment testing suite in the design of physical environments for the recovery of people with stroke. We also will have identified the significance of patient room type, social connectivity, nature exposure, and room size/expanse to people with stroke. This information can then be used to inform design guidelines in Australia for new and renovated health environments in hospital and rehabilitation settings.

ADHD is an impairing neurobiological disorder affecting over 300,000 young people in Australia. Up to 70% of children with ADHD experience sleep problems which contribute to substantially worse functioning. A number of studies have now demonstrated that sleep problems are amenable to intervention in young children with ADHD, with large improvements in sleep and child and family wellbeing. This study will extend this program to adolescents with ADHD given that sleep problems continue to be prevalent in adolescents are associated with poorer wellbeing. We recently completed a small pilot randomised controlled trial (DUHREC 2018-135) of a sleep intervention for adolescents (N=11) which demonstrated that the intervention is feasible to deliver to adolescents and their parents. We will now conduct a novel RCT to efficacy of the adapted Sleeping Sound intervention in adolescents aged 13-16 years with ADHD. It is hypothesised that compared to families in the usual care group, adolescents and parents in the intervention group will experience improved outcomes at 3 months post-randomisation for the following: 1. Adolescent sleep problems and sleep hygiene 2. ADHD symptom severity in adolescents 3. Adolescent wellbeing (i.e., mental health and quality of life) 4. Parent mental health

SUMMARY: Every day, many invasive devices are left in hospital patients after they are no longer needed for acute treatment, simply because they ‘might’ be needed or because staff forget to remove them. This places patients at unnecessary risk of hospital-acquired infections and other complications. This study will test the effectiveness of the I-DECIDED® device assessment and decision tool for improving the assessment, care, and timely removal of temporary invasive medical devices in acute adult hospital patients. AIM: To test the effectiveness of a decision-making tool (I-DECIDED®) in improving invasive medical devices assessment, care, and timely removal in acute hospital patients. SIGNIFICANCE: Each year in Australia, almost 10 million patients are admitted to hospital. Most patients receive at least one invasive device during admission, with many patients requiring multiple devices throughout their hospital stay. Many invasive devices are left in situ when no longer medically indicated, placing the patient at risk of healthcare-associated complications (HAC), increased morbidity and mortality, increased hospital length of stay and financial burden for the healthcare system, and personal and economic consequences for the patient. Regular daily assessment of all invasive devices for continued need and early detection of complications can prevent or mitigate many HACs. The proposed study will test the utility of the I-DECIDED® tool in guiding assessment, care and timely removal of all temporary invasive medical devices in acute adult hospital patients. The predicted outcome of implementing this simple but comprehensive tool is early detection of device complications, and fewer idle invasive devices and healthcare-associated infections. Success of this study will have positive consequences for hospital patients, healthcare providers, and healthcare systems.

The aim of this randomised controlled trial is to provide sustainability support to schools to sustain classroom teacher’s scheduling of daily Energisers (i.e., short 5–10 minute bouts of physical activity that occur during class-time) across the school week from baseline to 12 and 24-month follow-up. Schools will be provided a series of support strategies including, obtaining executive support, prompts and support to school champions, and provision of resources. Approximately 40 primary schools in Hunter New England, Illawarra Shoalhaven, Murrumbidgee and Northern New South Wales Local Health Districts will be randomly allocated to either an intervention group or a control group. The final trial endpoint is 24 months post baseline.

The aim of this study is to test the effectiveness of a new pillow designed to decrease the amount of time pregnant women spend sleeping on their back. This study will involve two conditions for each woman: one week using the new pillow and one week without the pillow, each ending with a night of overnight sleep monitoring. The sleep monitoring will (i) measure body position throughout the night to establish whether the new pillow is preventing back sleeping, and (ii) to determine if the pillow is comfortable and encourages better sleep. Importantly, we will (iii) perform fetal heart rate monitoring during the night to compare whether there are measurable differences in the baby's heart rate between these two settings. This study will help us to determine the impact of sleeping on your back during pregnancy, and whether we can encourage a safer sleeping position.

Hip fractures are a common presentation to hospital in the elderly associated with significant morbidity and mortality. To reduce hip fracture associated morbidity and mortality it has been recommended that patients receive frequent pain assessment, multimodal analgesia and adequate analgesia to allow mobilisation day one post-operatively. Part of a balanced multimodal analgesia plan includes performing a regional nerve block such as a femoral nerve block or a fascia iliac nerve block to reduce the requirement for opioid analgesia, potentially reduced rates of delirium, and facilitate early mobilization provided they do not cause motor weakness. The current standard in treatment for regional anaesthesia is a femoral nerve block, however studies have not shown a great clinical reduction in pain scores and there is associated quadriceps muscle weakness potentially delaying mobility after surgery. This had led to an interest in the development of a regional nerve block which produces a more significant reduction in pain without causing motor weakness. An anatomical study in 2018 explored the sensory innervation of the hip joint which has led to the development of the Pericapsular Nerve Group (PENG) block, first described in the literature in late 2018. The literature surrounding PENG blocks is so far limited to small case series and editorials, however the reported studies show potentially positive results of improved pain scores and potentially a reduction in quadriceps weakness. The aim of this feasibility study was to evaluate the impact of this new regional technique on pain scores, opioid use, and quadriceps strength compared to the femoral nerve block.

Identifying ways to support individuals with Alopecia Areata (AA) with mental health condition who have low levels of physical activity (PA) to overcome perceived barriers and enhance the perceived value of PA for preventing future relapse are crucial. There is an evidence-base for behavioural activation (BA) for depression, which focuses on supporting individuals to resume activities that have been avoided, but mental health practitioners have no specific training in promoting PA. We aim to evaluate an integrated PA together with Acceptance and Commitment Therapy (ACT), a self-help intervention to enhance mental health among individuals with AA. This study investigates, whether PA combined with ACT has a positive impact on study participants compared to stand-alone PA, ACT and control group, with regard to the self-reported secondary outcomes of: depression, anxiety, stress, and acceptance following treatment and at six-weeks follow up. The approach aims to enhance daily functioning through increased psychological flexibility. Whilst the therapeutic model behind ACT appears well suited to individuals with AA, there is a need for further research to test its effectiveness through intervention, particularly with regards to combining ACT with PA to increase mental health status in individuals with AA. This intervention is a randomised control trial (RCT) to evaluate the effectiveness of PA and ACT for individuals with AA to improve mental health.