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Nutritional challenges due to motor, cognitive and behavioural issues can occur after an Acquired Brain Injury, leading to poor nutritional intake and reduced quality of life (QoL). We aim to evaluate a co-designed meal-box solution for improving nutrition and QoL in ABI. Fifteen ABI families will receive the meal-box comprising recipes and ingredients for five meals. Feasibility, acceptability, QoL and nutritional intake will be assessed pre and post, using qualitative and quantitative measures. Positive results could lead to rapid implementation within the ABI community through our industry partner, with potential to extend the novel approach to other neurological conditions, thereby addressing a critical need.

This trial will evaluate a novel device, namely the Fetal Kicks device, for the detection of fetal movement in the third trimester of pregnancy. The study participants will be healthy women with uncomplicated pregnancies. The primary aim of the study is to determine that the Fetal Kicks Device is able to detect fetal movements and differentiate fetal movement from maternal activities. The secondary aim is to determine that the Fetal Kicks device is able to perform over an extended period of up to 12 hours.

A cluster randomised controlled trial to test a range of care enhancement strategies to increase the proportion of Aboriginal and Torres Strait Islander clients attending mainstream general practice with an up-to-date Health Check. Care enhancement strategies include: Study Champions at the practice to drive positive change, information for patients about the benefits and availability of Health Checks; reminders for eligible patients who are due for a Health Check, continuing professional education for practice staff, and data-based feedback provided to practices about the rates of Health Checks in their practice. Building on existing processes implemented in the participating practices and within the local Primary Health Network, care enhancement strategies will be tailored to the individual practices and the Aboriginal and Torres Strait Islander Communities they serve. It is hypothesised that the Care Enhancement strategies will lead to an increase in the proportion of Aboriginal and Torres Strait Islander patients who have an up to date Health Check and receive best practice care.

This study aims to determine whether advanced MRI scanning techniques can provide more detailed information regarding high-grade brain tumours in patients who have brain cancer. Who is it for? You may be eligible for this study if you are aged 18 years or older, you have been diagnosed with a grade 4 glioma or astrocytoma (brain tumour) and you are able to undergo an MRI scan. Study details All participants who choose to enrol in this study will be asked to undergo a single MRI scan. This scan is anticipated to take 60 minutes/hours. You will need to have a tracing agents injected as part of this scan (as you would usually). There are no extra blood tests as part of this study but you will be invited to contribute a blood sample for biobanking It is hoped this research will determine whether advanced MRI scanning techniques can identify biomarkers specific to brain tumours, and provide further information about the location and type of brain tumour for cancer patients. If these techniques are successful, the information provided by the MRI scans could assist doctors to determine which treatment options would be most effective for patients with brain cancer.

This study aims to examine the feasibility of a mobile application to collect follow up health data about Hodgkin Lymphoma survivors. Who is it for? You may be eligible to participate in this study if you are a patient aged 18 years or over, and must have received treatment for histologically confirmed classical HL according to the WHO classification. Study details Participants will enter their Hodgkin treatment and lymphoma response information, then complete a quesitonnaire on their current medical health including cardiac, respiratory, fertility, endocrine health. It is hoped that the results of this trial will help improve the lives of HL survivors.

The question of this study is: Would access to e-bikes combined with behavioural support enable sedentary adults to improve their levels of physical activity? The study aims at exploring the effects of e-biking combined with behavioural support on levels of physical activity. The hypothesis is that the MI-CBT supported intervention results in attainment of physical activity guidelines among previously inactive participants.

This program of research aims to safely reduce antibiotic use by supporting the implementation of best-practice Antimicrobial stewardship guidelines in general practice. These resources will support GPs treating adults with acute respiratory infections (ARIs). A UOW research team and collaborators, led by Profs Andrew Bonney and Judy Mullan, has been successful in being awarded a Medical Research Futures Fund grant (ID: MRF2029531) to conduct this research. This study is called the Optimal Implementation of Antimicrobial Stewardship in General Practice (OPTIMAS-GP) study. This pilot study will inform a larger randomised control trial.

In this study, we are interested in looking at the acute effects of the anti-Parkinson drug, levodopa/carbidopa (Sinemet®) on the rate of stomach emptying, blood pressure and abdominal blood flow after a sugary drink, and the relationship between the rate of stomach emptying and the rise in levodopa levels. The primary hypotheses underlying the study are that (i) a therapeutic dose of levodopa (200mg) / carbidopa (50mg) will slow gastric emptying in patients with mild to moderate Parkinson’s disease and (ii) this slowing of gastric emptying will be associated with an attenuation in the fall in blood pressure, and the rise in superior mesenteric artery (SMA) blood flow, after oral glucose.

The transition from hospital back into the community can be a difficult time for patients to navigate due to the involvement of multiple health professionals, medication changes and complex health care plans. These factors place patients at risk of medication-related harm during the transition of care (ToC) period. This study will use a prospective pre-post interventional study of a locally appropriate pharmacist-led interdisciplinary transition of care service for high-risk cardiology patients across three tertiary Queensland hospitals. We hypothesise that this will help to reduce 30-day medication related readmissions to hospital.

This study is a stepped wedge randomised controlled trial aimed at investigating the implementation and clinical effectiveness of multidisciplinary post-discharge bundles on preventing readmission for older people transitioning from hospital to residential aged care for the first time. This will be carried out at multiple hospital sites in three local health networks in South Australia. Eligible patients will be stratified according to their risk of readmission and will receive a customized post-discharge bundle of interventions based on their assessed risk. The outcomes are 30- and 90- day readmissions after the index discharge and length of stay out of hospital. Process evaluation will include the acceptability, adoption, feasibility and fidelity of implementation.