ANZCTR search results

This study is evaluating a proactive and structured telephone based intervention for carers of cancer patients. Who is it for? You may be eligible to join this study if you are aged 18 years or above and a carer of a newly diagnosed cancer patient attending chemotherapy or radiotherapy treatment with curative intent. Trial details Participants in this study will be randomly (by chance) allocated to one of two groups. Participants in one group will receive the new telephone based intervention. This is a proactive and structured outcall program of information and support, delivered by experienced Cancer Council Helpline nurses to carers. The Helpline nurse screens carers for distress and links them to a range of community based supportive care services as required. Carers in this group will be contacted by a Cancer Council Helpline nurse at 7-10 days post referral (Outcall One), four weeks later (Outcall Two), and three months later (Outcall Three). Participants in the second group will receive three telephone outcalls at the same timepoints as group one. The purpose of the calls is to remind participants about the availability of the Cancer Helpline. Participants who choose to contact the Cancer Helpline will not receive the Outcall program but the usual support provided by cancer helpline nurses. Carers will complete questionnaires at Baseline, 1 month and 6 months, and patients will be complete questionnaires at Baseline and 1 month, in order to evaluate carer burden, psychological health, carers’ ability to navigate health services, quality of life, unmet needs, and cost-effectiveness.

The aim of the research is to compare the established prectice of the Pain Clinic versus this intervention, consisiting of 5 hours of education to promote self management in persistent pain conditions. The study will be one of a randomised controlled trial pilot design; 2 care pathways; firstly usual care where patients will be assessed by a doctor and other allied health professionals. The intervention will be the education sessions followed by the option of patients attending clinic for consultations with the doctor and other health care professionals. The study will look at the research questions: 1. To see if pre-clinic education is a significant improved model of care compared with usual care, 2. To see the interaction between education sessions and medial intervention, 3. To monitor the changes in patients self management over time.

MiYoga has the potential to assist children with CP, training them to focus their attention on the present moment so that they can fully focus on activities in school, in therapy or when interacting with peers. At the same time, hatha yoga postures may provide additional physical benefits to complement the on-going therapy for children with CP. It is hypothesized that the MiYoga program will lead to improvement in the following child outcomes: 1) enhance sustained attention; 2) increase physical functioning – strength, balance and flexibility; 3) enhance present-moment awareness (mindfulness); 4) enhance in parent-reported child executive functioning in everyday life; and 5) decrease in parent-reported child behavioural and emotional problems; and 6) enhance parent-reported (if <9 years old) or child self-reported (if >9 years old) child quality of life. In addition, it is predicted that there will be improvements in the following parent outcomes: 1) decrease parent’s stress levels; 2) enhance child-parent relationship; and 3) enhance parent's psychological flexibility.

The aims of this study are to investigate the effects of altering the timing of food intake during Ramadan on: 1. The secretion of appetite regulating hormones and various metabolic parameters during a mixed-nutrient challenge test at dinner, 2. Body composition 3. Resting energy expenditure and respiratory quotient (to assess fat oxidation) in subjects with and without type 2 diabetes.

The long-term aim of this research is to develop a safe, effective and economical program that uses dexamphetamine to assist individuals in the establishment of a healthy pattern of diet and exercise for the treatment of obesity and maintenance of weight control.

Wholegrains are rich in nutrients and other substances with antioxidant activity that have the potential to benefit human health, in a similar way to the effects of fruits and vegetables. Wholegrain foods have been associated with reduced weight gain, slowly digested carbohydrates and improved heart health, particularly in studies of populations that consume certain wholegrains as a staple food. We wish to investigate if some positive effects can be identified and measured in people consuming specific wholegrains in a single meal. This study aims to demonstrate the immediate effects of eating a range of wholegrain breakfasts on appetite and blood levels of glucose, appetite hormones and antioxidants. Therefore, this study is a very important step towards building evidence for specific wholegrains as important foods in appetite control and disease prevention.

This study is evaluating how well six different types of ultrasound enhanced breast biopsy markers can be visualised using ultrasound on the day of surgery to act as a target for preoperative ultrasound guided lesion localisation with hook wire for surgical removal. Who is it for? You may be eligible to join this study if you have a mammographic abnormality requiring stereotactic vacuum assisted core biopsy. Trial details Following vacuum assisted core biopsy of one (or more) breast lesions, a participant will have one marker randomly (by chance) selected from six different marker types inserted into the biopsy site. Each participant may have more than one breast lesion that requires a biopsy in which case the next marker on the list will be used to ensure a different marker is used for each lesion. The performance of each marker (how visible it is on ultrasound and whether it stays at the biopsy site) will be assessed and compared to determine if any of these markers can be reliably used for preoperative lesion localisation using ultrasound guided hook wire insertion.

Menopause is the point in time when a woman’s menstrual periods stop. The years leading up to a woman’s final period is referred to as the “menopausal transition” and, on average, lasts 4 to 7 years. Previous research has found that about 1 in every 4 women experience symptoms of depression during this transition period. Some women may also notice changes that include: irregular menstrual periods, hot flushes, sleep disruption, night sweats, vaginal and urinary problems and low libido. Fortunately, the most bothersome features of the menopausal transition can be managed successfully, including the changes in mood. What we would now like to find out is if we can prevent changes in mood occurring altogether by addressing relevant risk factors for depression that might be present during the menopausal transition. This project requires the participation of midlife women who are experiencing symptoms consistent with the lead up to menopause. Eligible participants will be randomly assigned into one of two groups: Standard Medical Care or Standard Medical Care and a Health Coaching Program Women allocated to the health coaching program will have access to a health coach for a minimum of 8 telephone coaching sessions. The health coach will offer informational material on menopausal transition, depression and healthy lifestyle behaviours in addition to providing problem solving skills based training. A series of validated self-report measures will be mailed to all study participants at four time points (Baseline and at 8 weeks, 26 weeks and 52 weeks). These measures will collect demographic, lifestyle and clinical information. The primary outcome of this study is the diagnosis of depression (major depressive episode or dysthymia) according to DSM IV at follow up. We will test the following hypothesis: women randomly assigned to health coaching program will have a lower 12 month prevalence of depression than women randomly assigned to standard care.

The current study will evaluate an integrative internet-based approach to prevent mental health and substance use problems in adolescence. The intervention is known as Climate Schools Combined (CSC), and comprises of a twelve-lesson substance use course, and a six-lesson mental health course. Together the CSC program simultaneously targets alcohol, cannabis, depressive and anxiety disorders with the aim of reducing substance use and decreasing anxiety and depressive symptoms. The study is being run in 71 schools across QLD, NSW and WA. The CSC intervention will be compared to the individual Climate Schools Substance Use intervention, the Climate Schools Mental Health intervention, and the control condition. The RCT will be conducted over three years, with the delivery of the Substance Use course in Year 8 (except QLD students whom will receive the course in Year 9) and the Mental Health course in Year 9 (Year 10 for QLD). This study will be the first time such an intervention has been trialed, and is the first intervention designed to fit within the school syllabus to concurrently target substance use and mental health. Long term follow up: The approved extended long-term follow up will provide the first ever evaluation of the long-term effectiveness of combining universal approaches to the prevention of substance use, anxiety and depression and will examine the durability of intervention effects into the longer-term, over a 7-year period from adolescence to early adulthood.

Any missed injuries in trauma can cause prolonged hospital stay due to change in medical/surgical therapy, immobilisation, increase morbidity and mortality and increase cost of care. Trauma patients are referred to the physiotherapist for acute rehabilitation and ongoing care in the community when discharged from hospital. The aim of this study is to compare a medical tertiary survey and physiotherapy tertiary survey in identifying missed musculoskeletal extremity injuries after trauma admission. The patient recruitment period will be 12 months. When the eligible trauma patient is recruited to the study, the assessing physiotherapist will perform a tertiary survey as a part of an initial assessment to a physiotherapy treatment. Tertiary survey filled out by the physiotherapist will be compared with the treating trauma team. There will be 2 outcome groups in this study. Patients whose tertiary survey performed by physiotherapists prior to the admitting trauma team will be in P group. Patients whose tertiary survey performed by admitting trauma team prior to physiotherapists will be in T group. The outcomes of this study are: 1. Number of missed musculoskeletal injuries identified by physiotherapist and admitting trauma team 2. Comparison of new or missed and types of musculoskeletal injuries identified by physiotherapists 3. Number of tertiary surveys completed by physiotherapists earlier than the admitting trauma team.