ANZCTR search results

This project will examine a new treatment that is based on recent scientific findings about how children direct their attention to different stimuli that triggers anxiety. This treatment, called attention-focused treatment is delivered on a computer and takes about 30 min to complete. Children will complete the treatment 12 times over 3 weeks during sessions they can undertake at home. The treatment is thought to “work” because it helps children learn to control the focus of their attention on certain stimuli in the environment which in turn helps to prevent anxiety.

Approximately 40 % of elderly persons in South Australia are 'at risk' or are malnourished, and health service providers such as 'Meals On Wheels' offer elderly persons in the community a service which delivers nutritional meals to to assist them to live at home in their community for as long as possible. The broad aim of this pilot study is to compare the average amount of nutrients that elderly persons get from their 'Meals on Wheels' three course lunchtime meal to the amount of nutrients health professionals estimate you need for good health. Specifically, we would like to find out: 1) whether or not you are able to eat all of the food that is delivered each day 2) what things influence how much of the meal you eat 3) what helps or hinders you from eating the full meal and, 4) whether meals fortified with enough energy and protein to meet two-thirds of the an elderly persons estimated daily energy requirements and 100 % of their protein requirements are better than the current 'standard' MOW meal that aim to provide one-third of their energy and 50% of their protein needs, and if both meal types are indeed better than receiving no meal.

This study investigates the efficacy of an internet-based insomnia treatment program (SHUTi), compared to an internet delivered control program, as an adjunctive treatment to beyondblue guideline based treatment for reducing depressive symptom severity amongst men aged 50 and over with co-morbid depression and insomnia symptoms. Secondary aims are to determine whether adjunctive SHUTi improves insomnia and anxiety symptoms.

SCI results in severe impairment and is managed by a multidisciplinary rehabilitation approach. Unless sensitive and timely psychosocial assessment occurs, serious complications may not be identified or appropriately managed. This project will investigate the following within the Statewide SCI Units in Sydney: * develop and pilot a standardised psychosocial assessment schedule that can be used to monitor progress, set goals and detect psychosocial risks in people with SCI; * assess the efficacy of a multi-layered psychosocial cognitive behavioural therapy self-management rehabilitation package to be run as a service programme during inpatient rehabilitation in the SCI Units in Sydney

This study is trialling a new model of care for children and adolescents newly diagnosed with type 1 diabetes. Currently children remain in hospital for an average of 5-6 days while they receive initial stabilisation, commencement of insulin therapy and intensive education. Under the model being trialled, children will be discharged on day 2 after admission and will receive nursing support and education at home over a period of two weeks. They will continue to be under the care of an endocrinologist during this time and phone support will be available at all times. We will be assessing a range of clinical measures, patient satisfaction, knowledge, adjustment and quality of life in order to detemine whether this model of care is the same, better or worse than the existing one in terms of patient outcomes.

This study will investigate the quality of post surgical pain relief in patients who have undergone major gynaecological cancer surgery. Who is it for? You may be eligible to join this study if you are a woman aged 18 years or above, who is undergoing a laparotomy for gynaecological cancer procedures. Trial details Participants in this trial will be randomly (by chance) allocated to have their catheter inserted into one of three positions on the abdomen (i.e. abdominis plane, rectus sheath plane, or subcutaneous plane) at the end of their surgery whilst under general anaesthesia. The catheter is used to deliver pain-reducing medication and will remain in place for 48-72 hours post surgery. The total morphine consumption, pain, nausea and patient satisfaction will be compared amongst the three groups at 24 and 48 hours post surgery. It is hoped that the study will show that the patients who receive the rectus sheath block and transversus abdominis block will have more effective pain relief and require less morphine compared with the subcutaneous catheter group. Less morphine should reduce side effects and improve patient satisfaction.

An international collaboration of investigators has been established with the aim of assessing the benefits and risks of polypill-based care compared with usual care in populations at high risk of cardiovascular disease (CVD). Several trials are planned, as the effectiveness and economic impact of a polypill-based strategy may vary substantially between countries, given the varying influence of the health-care system within which the intervention is delivered. Primary outcomes for the individual patient data meta-analysis will include self-reported current use of antiplatelet, statin, and combination (>= 2) blood pressure lowering therapy at 12 months, and change in systolic blood pressure (SBP) and total cholesterol from baseline to 12 months. Non-inferiority margins of 3mmHg for SBP and 0.3 mmol/L for total cholesterol have been pre-specified. Secondary outcomes will include change in cholesterol fractions, diastolic blood pressure and creatinine from baseline to 12 months, quality of Life, new onset diabetes mellitus, mortality (cardiovascular, non-cardiovascular and all cause) and a composite outcome of cardiovascular events (including all coronary heart disease events, heart failure events leading to death or requiring hospital admission, cerebrovascular events and peripheral arterial events).

It is anticipated that the evidence gathered in this study will identify gaps in service delivery and inform policy directions such as investment into prevention strategies and/or better management of existing services.

The aim of this group randomised control trial is to evaluate a school-based physical activity and sedentary behaviour intervention for adolescent boys living in low-income communities who are ‘at-risk’ of obesity. The multi-component intervention will include a range of strategies to increase students’ participation and engagement in physical activity. The intervention will also include strategies to support parents to reduce their child’s time spent in screen-based recreation. Primary outcomes are body mass index, waist circumference and body fat (bio-electrical impedance analysis). Secondary outcomes include physical activity (accelerometers), screen time, fitness, resistance training skill competency, social and emotional well-being and sleepiness. Hypothesized mediators of physical activity and sedentary behaviour will also be explored. Assessments will be conducted at baseline, 9- and 18-months.

The aim of the ALIGN study is to better understand patient’s attitudes, beliefs and risks concerns towards their systemic medication.The ALIGN study deals with the collection of information only and is not designed for drug testing. You will also be asked to complete four types of questionnaires and one visual analog scale which will take approximately 30 to 45 minutes. You will have the opportunity to seal your answered questionnaires in an envelope so that they are not disclosed to your treating doctor.