ANZCTR search results

Acute heart failure is an important condition involving a high rate of death and complications. Currently, patients with this condition are admitted to hospital and follow a common management strategy. This study aims to determine whether it is safe and effective to discharge patients presenting to the hospital with acute heart failure to an out-of-hospital clinic-based management strategy instead of having to be admitted to hospital. Evidence suggests that with each admission, patients often lose part of their function and are at a high risk for the negative effects associated with being in hospital. This study therefore may support the use of similar discharge management strategies for future patients and improve their quality of life, risk of hospital-acquired complications, hospital costs and help to preserve their physical function. Study participants will either discharge to this out-of-hospital pathway or be admitted under usual care, and results between the two groups will be compared. Participants will be medically managed under these two pathways until they are fit enough to be discharged home as if they were admitted to hospital. Both groups will have daily reviews by clinical staff to ensure their safety.

This study is a randomized controlled trial, testing preventative/treatment strategies for managing vasovagal responses induced by intravenous cannulation in patients requiring cardiac CT with contrast. The strategies involve the employment of counter pressure maneuvers (hand gripping and/or adopting a lying down position) during intravenous cannulation. The researcher hypothesizes that the employment of counter pressure maneuvers (hand gripping and/or adopting a lying down position) will decrease the incidence of vasovagal response induced by intravenous cannulation.

The aim of this study is to determine the feasibility and effectiveness of a small-group 'Cognitive Behaviour Therapy for Insomnia' intervention for people with chronic pain who also have trouble sleeping. Participants from the Flinders Medical Centre Pain Management Unit will attend the small-group sessions with around 8 other people, once a week for six weeks, with four separate groups running. In this program, they will learn different ways to improve their sleep using sleep hygiene, stimulus control, sleep restriction, relaxation, and cognitive therapy. To determine how well the program works, researchers will measure participants' sleep, pain and quality of life prior to and immediately after the therapy, as well as 3 months later. If the program helps our participants, it could lead to more research to help others with similar problems.

This project delivers a training initiative to managers and staff in the residential aged care workforce to support staff in learning to recover from work-related burnout. Pre-, post-, and follow up surveys will be used to assess the effectiveness of the workshops and five weeks of self-reflection exercises after the workshops. We aim to establish the efficacy of the workshops and the workbook activities to improve aged care employees' resilience to work-related burnout.

Aim and participants: To evaluate the acceptability and the impact of an audio drama on the awareness and uptake of PrEP, compared to written information on a website, among Asian-born MSM in NSW, VIC and QLD. Methods: This trial will be conducted online. After participants consent to participate in the trial, and Qualtrics confirms that they are eligible, they will enter the trial. In the first part of the trial, participants will answer questions regarding their demographic characteristics, contact information, questionnaires related to HIV- and PrEP knowledge, attitudes toward PrEP and intention-to-use PrEP. Subsequently, they will be randomized to receive either the audio drama or written information page (Pan.org.au). The survey platform (Qualtrics) will assign participants to either arm randomly. After completing the intervention, they will complete post-intervention questionnaire. At one- and two months after the intervention, they will answer questions regarding the uptake of PrEP. Expected outcomes: The audio drama significantly increases the knowledge, intention-to-use, attitudes towards and uptake of PrEP and is more acceptable and engaging than PAN.org.au.

In this randomised, double-blind, placebo-controlled study, 200 adults aged 18 to 70 years with self-reported low mood will be randomly assigned to receive 14mg twice daily of a saffron extract (affron) or a placebo for 12 weeks. Changes in mood, sleep, and quality of life through the administration of validated self-report questionnaires will be assessed over time.

Palliative care patients’ capacity to participate in meaningful activities may be limited and this can negatively impact their quality of life. A personalised Virtual Reality (VR) intervention was trialled in an inpatient palliative care setting to establish the effects of multiple VR sessions on quality of life and symptom burden in patients. The intervention encouraged participants to visit their choice of memorable and desired places. Participants completed three 20-minute VR sessions and the effects of the intervention on symptom burden and quality of life were measured.

This a pilot study aiming to determine how appropriate and helpful is a telehealth program aimed to improving memory functioning in people who have a condition affecting their cognitive abilities (e.g., memory, attention, etc.). In other words, will this telehealth memory intervention lead to improvements in memory problems and other psychological factors (e.g., satisfaction with participation in social roles). The structured group rehabilitation program consists of six weekly two-hour sessions, covering psychoeducation about the impact of neurological conditions on memory, training in compensatory memory strategies, and education on the influence of lifestyle factors like diet, exercise, and sleep. The sessions involve interactive activities and homework tasks to practice and apply the learned skills in daily life.

This is a randomised controlled trial comparing the effectiveness of an online telehealth program aimed to improving memory functioning in people who have a condition affecting their cognitive abilities (e.g., memory, attention, etc.) with a waitlist control. In other words, will this telehealth memory intervention lead to improvements in memory problems and other psychological factors (e.g., satisfaction with participation in social roles). The structured group rehabilitation program consists of six weekly two-hour sessions, covering psychoeducation about the impact of neurological conditions on memory, training in compensatory memory strategies, and education on the influence of lifestyle factors like diet, exercise, and sleep. The sessions involve interactive activities and homework tasks to practice and apply the learned skills in daily life.

This is a semi-randomised controlled trial that compares the effectiveness of an online telehealth versus face-to-face program aimed to improve memory functioning in people who have a condition affecting their cognitive abilities (e.g., memory, attention, etc.). In other words, will this telehealth memory intervention lead to improvements in memory problems and other psychological factors (e.g., satisfaction with participation in social roles). Participants will have the option to either elect do the program over telehealth only, or telehealth/face-to-face at Westmead Hospital. The structured group rehabilitation program consists of six weekly two-hour sessions, covering psychoeducation about the impact of neurological conditions on memory, training in compensatory memory strategies, and education on the influence of lifestyle factors like diet, exercise, and sleep. The sessions involve interactive activities and homework tasks to practice and apply the learned skills in daily life.