ANZCTR search results

This trial is a before and after study design on one group of patients to assess the effects of Clinical Pilates intervention. Patients presenting to the Physiotherapy Department either through self-referral or referral from a MO or Specialist will be assessed for suitability for inclusion in the trial and will be given the appropriate information and informed consent will then be sought. The primary aim of this study is to assess the effectiveness of Clinical Pilates on pain and function in patients with Chronic Low Back Pain. The hypothesis is that there will be clinically and statistically significant positive outcomes based on current clinical practice in the physiotherapy department at HMAS Kuttabul.

Vapocollant spray is used overseas to decrease the pain of intravenous cannulation. However, no randomised controlled trial has been reported to provide evidence for this.

This study investigates whether a new form of treatment (NET) has a beneficial effect on tender or painful trigger points. Trigger points are locations on a muscle surface which are abnormally tender and are a source of self-perpetuating and continuing pain. This study looks at trigger points in the neck region. Participants will be assessed for the presence of trigger points. They will be given one course of NET treatment. They will return after 3 days to have their trigger points assessed for any change in their tenderness and the degree of neck pain. The treatment group results will be compared to a control group who receive a sham treatment which has no therapeutic value.

The aim of the study is to test the scientific theory that persons can be reinfected with H.pylori on multiple occasions. If so, then a genetically modified H.pylori strain may be the ideal delivery system for live oral vaccines.

Hypothesis/research questions: That mothers can be effectively coached on a number of simple measures that will improve skin barrier function in their infants that will reduce the incidence of Atopic Dermatitis And that improvement in skin barrier function will reduce the incidence and severity of atopic dermatitis in the short term and ultimately, food allergy and asthma associated with atopic dermatitis And that null mutations in the fillagrin gene increase the risk of future development of atopic dermatitis, food allergy and asthma associated with atopic dermatitis. And that null mutations in the fillagrin gene are predictive of infants who stand to obtain the greatest benefit from interventions to improve skin barrier function. To test our hypothesis we propose to conduct a prospective randomised controlled study. The study will investigate the impact of a number of simple intervention measures on epidermal barrier protection as measured by transepidermal water loss in infants and young children. In addition, this randomized, controlled study will measure the prevalence and severity of atopic dermatitis.

This study has been designed to assess whether a ventilation strategy which maintains alveolar patency by the application of recruitment manoeuvres and elevated PEEP and which limits airway pressures by allowing permissive hypercapnia will reduce lung injury as assessed by serum cytokine levels.

Previous research has demonstrated that the use of a simple advance notification letter preceding an invitation to participate in bowel cancer screening resulted in a significant increase in population participation compared to no advance notification of invitation. This study further explores the value of advance notification by comparing screening participation between 3 groups: 1) using an enhanced version specifically addressing known barriers (aversion for collecting faecal samples, lack of knowledge about bowel cancer, low perception of the value of screening); 2) a simple advance notification letter and 3) a control group not receiving advance notification.