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Mechanisms and treatment of chronic cough
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Improving intestinal function after surgery
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Left ventricular diastolic function in lean and overweight subjects.
Expand descriptionThis cross-sectional (snapshot) study aims to measure the relaxation function of the heart (using ultrasound) in a group of people who do not have diabetes, who are of varying weight and body size (ranging from lean to overweight).
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The effect of CoEnzymeQ10 on vascular function in type 2 diabetes mellitus: a pilot study.
Expand descriptionThis pilot (preliminary) study aims to determine if taking supplements of CoEnzymeQ10 (a vitamin with antioxidant properties) improves the relaxation function of artery blood vessels in people with type 2 diabetes.
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Randomised placebo controlled study on the safety and efficacy of a herbal tonic for cessation of smoking - five week pilot study
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An Open-Label, Multicentre Study to Evaluate the Duration of Clinical Remission of Two Courses of Weekly Intramuscular administration of AMEVIVE (alefacept) by evaluating the time to retreatment with AMEVIVE or an alternative systemic therapy in patients with chronic plaque psoriasis in the context of standard dermatological practice
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Australian screening mammography decision aid trial: A decision aid for women aged 40 thinking about starting mammography screening
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The Hydromorphone Trial
Expand descriptionHydromorphone is an opiate drug quite similar to morphine and is widely used to treat pain after surgery. A recent idea is to use a patient controlled technique which allows the patient to self-administer the drug as they need using a nasal spray. Previous studies show the absorption of hydromorphone through the nasal mucosa is rapid within a few minutes and that pain relief is very effective. The advantage of this route of delivery is that it avoids the use of intravenous drips. In this study we will be comparing the intravenous route of administration with what happens after a similar dose of hydromorphone is given intranasally. This will help to detemine the most appropriate way to prepare the nasal drug and the best dose to give with each spray. Postoperatively patients who are using patient controlled intravenous analgesia will be given a dose of hydromorphone for pain before they are allowed to start using their pump. All patients will get an intravenous and an intransal dose 12-24 hours apart. The order of which comes first will be randomly allocated. Blood wil be taken from a previously sited cannula at intervals before and after doses to measure levels. At all times good pain relief is guaranteed by use of the fentanyl PCIA.
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A prospective multi-centre evaluation of clinical and economic outcomes of Double-balloon enteroscopy in patients with identified small bowel pathology.
Expand descriptionEvaluation of clinicaL and economic impact of double-balloon enteraoscpy in patients with identified small bowel pathology
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Investigating cognitive effects of aromatherapy on people with dementia living in residential care facilities
Expand descriptionThe study design was a randomised, controlled trial. Repeated measures were taken at baseline, 3 points during treatment, and after a wash-out period at the end of the trial. The participants and the person doing the cognitive testing and data analysis were blinded to the treatment allocation, and the staff administering the treatment were blinded as to which of the treatments was the active. The trial will be carried out in parallel groups, with staggered starting times to allow adequate time for the cognitive testing.