ANZCTR search results

This study aims to evaluate the pain self-efficacy, or confidence, of participants undertaking a ten week group exercise program for people with chronic pain. Specifically this study aims to answer the following questions: 1. Does the pain self-efficacy of participants attending the Physiocise Foundations program change between the initial assessment, the end of the ten week program and the 3 month follow-up? 2. Does participants level of confidence to perform set tasks at home change between weeks 1, 5 and 10 of the program? 3. Are there any associations between participants’ outcome scores for Goal Attainment Scale, and their pain self-efficacy, level of disability and fear avoidance scores?

This pilot study will assess the feasibility and effect of pelvic floor muscle training (PFMT) on post-operative UI in men undergoing RP at Western Health. WHO IS IT FOR? Men with a planned surgery date for radical prostatectomy who have been admitted to the Western Continence Service (WCS) at Western Health. Men who are English speaking background and have not experienced any bladder leakage in the 12 months prior to their operation can participate. 30 men will be recruited to this study. STUDY DETAILS Men will attend to participate in the study prior to having their surgery. This randomized controlled trial (RCT) allocates men to one of two groups: The functional training group where they are asked to do a series of functional exercises such as steps ups and lunges with a pelvic floor muscle pre-contraction; or the standard care group where they perform static pelvic floor contractions as part of their program. Men will complete questionnaires and pad weights at 4, 12 and 26 weeks after their surgery to help collect data. This study will assess the feasibility of this study and the potential for development of a larger scale study. It will also assess the effect that the above exercises have on post-operative UI.

The aim of this RCT is to determine if there are any benefits of placing dental implants into sites that have previously received alveolar ridge preservation (ARP) when compared to conventional implant placement protocol. This study will be carried out on patients recruited from a specialist clinical practice who are referred for single implant replacement in the aesthetic zone (teeth 13-to-23) and who meet the inclusion criteria.

The purpose of this study is to compare the clinical performance (defined by visual acuity measurements, subjective response, lens surface characteristics and ocular physiological characteristics) of a commercially-available (Europe and Japan) contact lens (SEED Pure) against commercially-available (Australia) contact lenses (Proclear and Vita). To achieve this, participants will wear one of these for 3 months on a daily-wear basis with monthly replacement. All participants will use Alcon Puremoist multipurpose disinfection solution. Our hypotheses are there will be no difference between lens types for visual acuity, subjective response, lens surface characteristics and ocular physiological characteristics.

Purpose of the Study This study seeks to evaluate the effect of a slowly increasing or decreasing doses of PBMt (number of sessions per week) on the signs and symptoms of Parkinson’s disease whilst participants may also be receiving usual care physiotherapy. The doses will be slowly altered each four weeks and there will be four dose variations evaluated. We will measure the effects of the treatments in two ways throughout this period: a) at home by observations made by the chosen significant other/carer b) in the clinical setting with specialist and physiotherapy evaluations. Also, there will be two different forms of medical light trialled: a) one that could eventually be recommended for home use, and b) one that is a clinic based therapy. In this study, the medical light will be applied by a trained physiotherapist to the head (in Brisbane arm of trial) or other parts of the body (spine and abdomen in Sydney arm of trial), and in combination (head, spine and abdomen) in the Adelaide arm. In the Brisbane, participants will be randomly allocated into receiving one of two forms of light device. In the Sydney arm of the trial, only one device will be trialled and evaluation of the gut microbiome will be added to the outcome measures. In the Adelaide arm, the two devices will be used and the gut microbiome will be analysed as well.

Background: Depression is at least three times more common in people with coronary heart disease (CHD) but is underdiagnosed and inadequately treated. Psychological treatments are preferred by most patients with depression but are complex and costly to deliver. Behavioural activation (BA) is a simpler alternative that could potentially be delivered by therapists (physio, occupational) as an add on to cardiac rehabilitation. Objective: To determine the feasibility of providing therapist delivered BA as an adjunct to cardiac rehabilitation to patients with depression and coronary heart disease. Design: Feasibility – before and after – trial. Methods: Patients referred to the North East Rehabilitation Center for cardiac rehabilitation program will be screened for depression using the PHQ-2. Those with a score >3 (indicative of at least mild depression) will be invited to take part in the study. Patients already receiving depression treatment (either medication or psychological), who are alcohol or drug dependent, are suicidal, have cognitive impairment or psychosis will be excluded from the trial. Key outcomes: 1. To determine the number of patients we need to ask to participate in the trial to get one to consent, 2. Proportion of patients who complete treatment (and the number of sessions they attend), 3. Completion of outcome measures, 4. Acceptability of behavioral activation as part of cardiac rehabilitation, 5. Proportion of patients that complete the trial. Unexpected harms associated with combining behavioral activation and cardiac rehabilitation will be closely monitored. Discussion: This study will provide evidence on the feasibility of conducting a trial to evaluate the efficacy of incorporating behavioral activation as part of routine cardiac rehabilitation for depressed patients with coronary heart disease.

To compare the feasibility, acceptability and impact of installing sit-stand workstations plus advice, with or without exercise, on back pain and sitting time in office workers at risk of low back pain.

The research project aimed to compare body composition and maximal strength and power performance in Powerlifting and Olympic Weightlifting exercises in the same group of resistance-trained participants exposed to 3-months ketogenic diet and 3-months of usual control diet.

FT011 is being investigated as a potential drug to inhibit scar formation in the eye after surgery. The main aim of this study is to assess whether FT011 can enter the eye, as well as determine the safety of FT011 in the eye.

This study seeks to establish a reference range for a urinary kryptopyrrole test produced and conducted by SAFE Analytical Laboratories Pty Ltd ("the test"), This study is aiming to provide suitable data to enable registration of the test on the Australian Register of Therapeutic Goods (ARTG). Four parts to this study have been designed to correlate the urinary kryptopyrrole levels with health and disease states as observed in adult populations.