ANZCTR search results

These search results are from the Australian New Zealand Clinical Trials Registry (ANZCTR).

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31611 results sorted by trial registration date.
  • Optimal timing of solid food introduction to infants at high risk of developing allergic disease.

    Food allergies are common and result in a significant burden to families and the health care system. One approach to prevent food allergies may be to introduce specific foods earlier than currently recommended. The study will compare early regular introduction of egg from 4 months compared to the more common practice of egg avoidance until 8 months of age. If successful at reducing egg allergy, this approach will have a significant impact on reducing the burden of allergic disease.

  • Promoting Physical Activity and Preventing Obesity in Economically Disadvantaged Schools: The Physical Activity Leaders Program for Adolescent Boys

    The aim of this study is to evaluate the effects of a physical activity program for low-active adolescent boys in economically disadvantaged secondary schools. The study will assess changes in physical activity and health-related fitness over a 6-month period.

  • Specific Treatment of Problems of the Spine (STOPS) Trials: Effects of specific physiotherapy functional restoration and advice versus advice alone for people with sub-acute non-reducible discogenic low back pain.

    The primary aim of this trial is to compare the outcomes and adverse events of two different physiotherapy treatment approaches for people with lumbar non-reducible discogenic pain. A secondary aim is to determine the perspectives of participants on the functional restoration program utilised in the trial.

  • Cognitive training for 'at risk' older people

    This trial will assess the effects of a 'healthy brain ageing program' for older adults at risk of cognitive decline and/or dementia. It incorporates both cognitive training as well as information that will equip participants with knowledge regarding preventative risks for depression and cognitive decline. It is expected that those who participate in the treatment will improve in terms of memory functioning.

  • A randomized clinical trial of continuous positive airway pressure (CPAP) in the treatment of acute cardiogenic pulmonary oedema (APO) patients in the pre-hospital setting

    Purpose of trial is to compare Continuous positive airway pressure (CPAP) versus conventional therapy of inspired postive pressure ventilation with bag valve mask.

  • Does epidural analgesia affect outcome after lower limb bypass surgery?

    Epidural anaesthesia has a mitigating influence on adverse metabolic effects that may influence the outcome from surgery. This trial was designed to investigate whether extending epidural analgesia into the postoperative period improves outcome from high risk vascular bypass surgery

  • A comparison of oesophageal Doppler with arterial pressure waveform derived cardiac output and stroke volume variation for the assessment of haemodynamic state in adult patients undergoing major surgery.

    This study looks how accurately some monitoring systems perform during major surgery. One device looks at flow in a major artery and uses a probe inserted into the gullet under general anaesthesia. The other device/s reads a signal from a standard line inserted into a small blood vessel in your arm to record the blood pressure. The aim is to see whether these devices measure changes in blood flow accurately during surgery. As these devices are relatively new, it is important to identify wihch monitor is most accurate in helping the anaesthetic doctor to make potentially important decisions. It is an observational study and does not change your anaesthetic in a significant way.

  • Three Techniques for Establishing Component Alignment in Total Knee Reconstruction: A Randomised Clinical Trial

    The purpose of the study is to determine which surgical technique provides the best alignment for total knee replacements The null hypothesis is that all techniques are equally good.

  • Impact of a Liver Failure Service for patients with cirrhosis

    A six-month study exploring the effectiveness of a a liver failure program for patients who have cirrhosis of the liver and are admitted to hospital with a liver-related issue.

  • Correlation of preoperative combined positron emission tomography/computed tomograpy with surgical and histopathological findings for patients with endometrial cancer

    Prospective study to be conducted at Monash Medical Centre Moorabbin Melbourne Victoria. The aim is to determine whether Positron Emission Tomography combined with computed tomography (PET/CT) is able to predict the stage and spread of uterine (Endometrial) Cancer when performed preoperatively. A further aim is to determine whether its use is beneficial in guiding further treatment of the patient, With our hypothesis being that PET/CT is useful in ensuring appropriate management of the woman with uterine cancer

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