ANZCTR search results

To examine the safety and tolerability of Everolimus in combination with 5-azacitidine in Acute Myeloid Leukaemia.

Adolescents with diabetes display limited joint mobility. Because of the association with high pressures under the feet, poor sensation and foot ulceration with disease progression, limited joint mobility assessment is a standard procedure in diabetic foot care. Clinical interventions to reduce high pressures under the feet include orthoses, footwear and surgical correction. While stretching has been reported to improve ankle joint range of motion in the general population, limited evidence is available for individuals with diabetes. The evidence for calf stretching in adolescents where prevention of contractures and high plantar pressures in the early stages of disease may be most beneficial have not been investigated. This study will use a randomised control study to investigate the efficacy of stretching on the ankle and big toe joints to reduce high pressures under the feet and contractures of the ankle and foot joints.

The overall aims of the project are to design, implement and evaluate an educational campaign, known as MindWise to help raise mental health literacy in higher education students and staff. Data will be collected on mental health problems (anxiety, depression and alcohol misuse), knowledge of and beliefs about mental health problems, stigmatizing attitudes, self-help and help-seeking behaviours at baseline, at the end of the 2010 academic year and the end of the 2011 academic year. Data will be collected via telephone interviews carried out by the Social Research Centre.

Selected patients with signs of pudendal neuralia and low back pain treated with physiotherapy consisting of mobilisation and exercises directed to the lumbar pelvic region.

This study investigates the effects of branched chain amino acids and/or Synbiotics, a mixture of probiotics and prebiotics, on the level of hepatic encephalopthy in patients with cirrhosis using using computerised psychometric test and trail making test It also investigates the effects of branched chain amino acids and/or Synbiotics, a mixture of probiotics and prebiotics, on inflammatory process, quality of life, frequency and duration of hospitalisation, food intake and body composition.

An Early Intervention Program which targets preschool aged children who are at a high risk of developing anxiety. Efficacy of the program will determine whether prevention steps in the early years have a part to play in reducing current symptoms and also associated risk.

The aim of the present study is to examine the efficacy of a group modified cognitive behavioural therapy (CBT) intervention on reducing anxiety and internalizing disorders in adolescents with high functioning autism spectrum disorder. In addition to a longitudinal follow-up, this study seeks to determine the impact this treatment has on family quality of life.

The purpose of the study is to answer three key research questions: 1. What effect does supervised, progressive resistance training (PRT) have on the number and incidence of falls in older adults with impaired balance? 2. What effect does supervised, PRT have on balance in older adults with impaired balance? 3. What effect does supervised, PRT have on self-reported quality of life of older adults with impaired balance?

This trial investigates the effect of hip surgery on sleep apnea severity. We hypothesise that sleep apnea will worsen in the immediate postoperative period, due to factors such as sedative medications, intubation and the requirement to lie on the back after surgery.

This is a nutrition program for women after breast cancer treatment, called The Muscle Mass, Omega-3, Diet, Exercise and Lifestyle (MODEL) Study. Who is it for? You can join this study if you are a woman who is a breast cancer survivor. In other words, you have successfully completed surgery, radiotherapy and/or chemotherapy with no sign of existing disease, and treatment was completed less than 12 months ago. You must be aged from 18 to 80 years. Trial details Participants will be randomly allocated to one of three groups. One group will take a nutritional supplement of 3g/day of Omega-3 fatty acids for 6 months. A second group will take Omega-3 in conjunction with 12 weeks of Cognitive Behavioural Therapy (CBT) healthy eating and exercise education. The third group will undergo the CBT program and take placebo capsules. Participants will be monitored at the start of the program and at 12 and 26 weeks. The study aims to measure any changes in lean body mass, changes in inflammation and changes in quality of life