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Fat emulsions are an essential part of parenteral nutrition (PN) combining a high energy load with an essential fatty acid (EFA) intake.The primary purpose of this study is to test the safety and efficacy of new fish oil based intravenous fat emulsion (SMOFlipid) as compared to traditional olive oil based intravenous fat emulsion (Clinoleic). This study will specifically look at plasma and red cell fatty acid levels particularly Docosahexaenoic acid (DHA) which plays an important role in development and vision of newborn babies and also oxidative strss levels (F2-isoprostanes) before and after the intervention in a randomised controlled trial.

While basal-bolus insulin management is preferred over sliding scale for glycaemic control of hospitalised diabetics requiring intensified glycaemic control, there are no recommended basal-bolus approaches, and little data comparing the 2 approaches. The development of our basal-bolus approach requires testing to ensure its clinical efficacy, and that it is actually a better practice than sliding scale insulin. The main comparator will be the mean daily glucose readings taken from the routine four times daily capillary blood glucose measurements.

Timely and accurate discharge summaries play a critical role in the continuity of patient care between hospitals and primary care physicians or general practitioners in the community. The objective of this study was to examine the effectiveness of delivering of computer-generated discharge summaries to general practice by email, fax, post and patient hand-delivery.

The primary aim of the this trial is to compare the outcomes and adverse events of two different physiotherapy treatment approaches for people with sub acute low back pain with or leg pain. A secondary aim is to determine the perspectives of participants on the manual therapy program utilised in the trial.

Study aims to identify whether there are significant differences between the outcomes achieved through a collaborative intervention in a sample of patients diagnosed with depression, T2DM and CHD and usual care.

This study will determine: (i) to what extent people with COPD choose to use a wheeled walker in day-to-day life; (ii) whether providing a wheeled walker for use in their home and community increases their level of daily physical activity and; (iii) whether use of a wheeled walker improves quality of life or increases an individual’s confidence to walk (i.e. they feel less fearful of falling). A total of 30 patients with COPD will participate in the study. On the completion of a pulmonary rehabilitation program, people with COPD that are considered appropriate for a wheeled walker will complete two consecutive four week “periods”. During one of these periods, but not the other, they will have a wheeled walker provided for use during daily life. Measurements of wheeled walker usage, daily physical activity, quality of life and fear of falling will be collected on completion of each four-week period and compared in order to determine the effect of a wheeled walker on these outcomes.

Currently fasting blood glucose (FBG) and glycated hemoglobin (HbA1c) are used to assess diabetes control. However high peak blood sugar levels after meals probably contribute more to the complications of diabetes than high average levels. There is very little known about the effects of meal composition and carbohydrate distribution on overall blood sugar control. This study will contribute to our understanding of the role of diet in the management of type 2 diabetes and help in the development of evidence based dietary guidelines regarding carbohydrate distribution. To investigate the effect of three identical meals on diurnal blood glucose excursion,tretment 1,breakfast lunch and dinner. To explore the effect of withholding carbohydrates at first meal after a prolonged (overnight) fast on the impact of carbohydrate ingestion at lunch time,treatment 2,breakfast lunch and dinner.Hence there are 2 arms to the study each diet is investigated for one full day.A gastric emptying breath test is performed on the first day in both weeks. To determine the rate of gastric emptying when comparing a standard lunch following either a carbohydrate containing breakfast or a breakfast with no carbohydrate.

In this study, we will be continuing to follow participants recruited for the research project “Preventive Strategies for Early Childhood Caries from Antenatal to age 24 months" Princess Alexandra (PA) Ethics no. 2006/145, and Australian Clinical Trials Registry (ACTR) registration number ACTRN012606000356561 who have undergone preventative methods of education, home visits and toothbrushing with low-dose fluoride toothpaste, 0.2% chlorhexidine gel and casein-phosphopeptide amorphous calcium phosphate (CPP-ACP, ToothMousse). The effectiveness of these strategies will be assessed through - Pre- and post questionnaires - microbial analysis for the presence of decay causing bacteria - dental screen analysis for all participants at age 3 and 4 - statistical analysis of data for case and control groups

This study is testing a new treatment for sore throat called flurbiprofen micro granules. Flurbiprofen lozenges are approved by the Australian health authority, the Therapeutic Goods Administration (TGA) for the relief of pain, swelling and inflammation due to severe sore throat. In this study, tiny granules of flurbiprofen will be tested to determine if they too are effective in the relief of sore throat.

Echinacea has shown immuno-modulating effects and this study will investigate the efficacy of an echinacea preparation in the prevention of respiratory and other symptoms associated with air travel.