ANZCTR search results

We hypothesize that bacteraemia occurs in a small proportion of people following needle puncture of the tracheal wall during Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) of mediastinal lymph nodes. The purpose of the study is to confirm the proportion, and also to identify the likely bacteriologic agents. This will allow appropriate guidelines of use of antibiotic prophylaxis and choice of empiric antibiotic therapy for those developing clinical infection following EBUS-TBNA

Low-low beds are a type of bed that can be lowered closer to the floor than regular hospital beds. This study investigates whether providing some of these low-low beds to hospital wards can assist in preventing accidental falls.

After a hospital stay some older people will be accepted on the Transition Care Program into a bed based place. They may go to a hostel or nursing home for a few weeks after completing their inpatient stay. These people may receive physiotherapy treatment while they are staying there with the aim of helping them to assist them to get as well as possible. As part of this study some of these people will be offered more physical activity and additional supervision whilst exercising. The aim of this project is to see whether this will make any difference to where the people go at the end of their stay - to their home or long term in residential care. Approximately 50 people will take part in this study over a period of two years. The study will take place in Bendigo.

The anti-inflammatory properties of fish oil are well documented. Hip fracture is common and patients suffer significant unintentional weight and muscle loss leading to poor outcomes. An inflammatory response to the injury is a plausible mechanism for the lack of response observed in these patients when provided with best practice nutrition. This study aims to reduce the weight loss suffered by hip fracture patients by prescribing an intervention of individualised nutrition support and fish oil.

The purpose of this study is to explore the efficacy, acceptability and compliance associated with using the SMART device for weight loss in overweight and obese adults, and to gain experience with this device in Australia. Hypothesis: The use of the device will reduce oral food intake and lead to a substantial weight loss when combined with dietary advice and a physical activity program

Omega-3 oils are known to have benefits for joints, skin and the circulation. There are reasons to believe that they may help improve bone health in people with low bone density. This study aims to examine the safety, effectiveness and acceptability of an omega-3 oil, docosohexanoic acid (DHA) when given for 1 year in combination with calcium and vitamin D.

This is a prospective study looking at treatment preferences, decision making, decision regret, patient preferences, side effects and disease outcome in pre-menopausal women under 47 years with low-risk early breast cancer. Recruitment is over 24-months at multiple sites in Australia and patients with "low risk" breast cancer will be invited to participate after they have chosen their treatment.

Purpose to determine if different oxygen therapies for patients having AECOPD in the pre-hospital setting have different outcomes (ie. Mortality, length of hospital stay, requirement for ventilation, difference ABGs)

Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in 40+ year olds in Australia and much care is directed at dealing with the consequences of the disease at an advanced stage. Many of the risk factors (high cholesterol, high blood sugar, hypertension, obesity, inactivity, cigarette smoking) though modifiable are often undiagnosed and hence untreated. Even when diagnosed and when a treatment plan is in place, patient adherence to the treatment guidelines may not be as rigorously followed as expected. For many, the general practitioner (GP) is usually the point of first contact with the health system. GPs are well positioned to offer positive health messages and treatment options that can influence the health of their patients. This can be achieved through a combination of involving patients more in their own risk factor management and providing greater primary care support (GP and practice nurse) thereby stimulating the motivation for patients to increase their adherence to clinical guidelines. In light of this we undertook the “Fremantle Primary Prevention Study” over the last 18 months, in 1200 men and women aged 40-80 years recruited through 3 general practices in Perth. This study aims to show that while a significant proportion of the community are already known to have cardiovacular risk factors, GPs and their practice staff are ideally positioned to assess the extent of this potential morbibity and institute treatment modalities and exercise programs to reverse and modify them.