ANZCTR search results

Patients with complicated grief will be randomly allcoated to a combiantion of group and individual therapy. Patients will receive either 10 sessions of cognitive behaviour therapy with exposure therapy, cognitive behaviour therapy without exposure therapy, or skills training.

This study will randomly allocate patients with PTSD to either standard cognitive behaviour therapy (CBT) or to cognitive behaviour therapy (CBT) that does not provide prolonged exposure. Instead, the cognitive behaviour therapy (CBT) will include brief exposures to trauma memories integrated with cognitive restructuring.

Palliative care services strive to support patients to die within the setting of their choice, usually home, with optimal symptom control and a pattern of care that is supportive of caregivers. Palliative care professionals appreciate that, due to resource constraints, the likelihood of patients remaining symptomatically well managed at home depends upon input from lay carers, usually family members. This study has been designed to evaluate an intervention that supports and educates caregivers to safely and appropriately administer subcutaneous medications for the purpose of symptom control. The study has two components: 1. To implement a standardised education and support package for lay carers living in urban, regional and rural settings within Queensland and to evaluate that package across the domains of content, efficacy, safety and satisfaction. The package will be evaluated using two lay carer questionnaires. The first will be completed immediately following the delivery of the standardised package. The second will be repeated four weeks after their completion on the trial. The questionnaires will rate the usefulness of the education delivered and resources provided. 2. To identify possible differences in outcomes for lay carers, in terms of confidence, safety, satisfaction, and stress measures with the preparation and injection of subcutaneous medications across three different conditions. I. The lay carer prepares, labels and stores daily breakthrough medications for subsequent injection II. A registered nurse prepares and labels daily breakthrough medications for subsequent storage and injection by lay carers III. A clinical trial pharmacist prepares and labels daily breakthrough medications for subsequent storage and injection by lay carers. Differences in outcomes will be measured using surveys and Likert scales and statistically analysed. In addition, caregivers will be invited to record their experience in a daily diary.

This study will compare the safety and tolerability of a treatment for neuroendocrine tumours in two groups: one group is injected by a health care professional the other group will inject themselves or have a carer/partner inject.

This study aims to find out the normal level of D-Dimer during different stages of pregnancy and to assess whether D-Dimer levels are associated with various abnormal outcomes of pregnancy for women in Tasmania.

It is hypothesised that clubs participating in the accrediation program will have a signficant reduction in harmful alcohol-related behaviour over the intervention period. In contrast, it is expected that clubs not participating in the intervention will not have a significant reduction in harmful alcohol-related behaviour over the same period of time.

The research program will test the hypothesis that increasing dietary protein to at least 1.3 g/kg/d through the consumption of lean red meat on most days of the week, when combined with regular exercise (progressive resistance training), in a vitamin D replete state, can reduce markers of inflammation and enhance muscle mass, strength, power and functional performance in elderly women compared to resistance training alone.

2 randomised controlled trials have demonstrated the safety and efficacy of cabergoline to limit the development of ovarian hyperstimulation syndrome (OHSS) in women at risk of this condition undergoing IVF treatment. This prospective observational study aims to look at the incidence of the development of the condition and any side-effects caused by the administration of cabergoline by women at risk of OHSS.

Non Alcoholic Fatty Liver Disease (NAFLD) is a well described complication of type 2 diabetes. It is a disease with a broad spectrum of severity with the most aggressive form of it Non Alcoholic Steato-Hepatitis (NASH) often progressing to liver cirrhosis. Up until now the liver biopsy had been the gold standard in determining the stage of liver disease (or fibrosis) in such patients however a liver biopsy is costly, invasive and associated with complications including death. In recent years a new technique called fibroscan (Transient Elastography) has been validated as a non-invasive method of measuring liver fibrosis .Fibroscan(Transient Elastography) works by transmitting a vibration through the liver with the aid of ultrasound , this gives an impression of how stiff the liver is and liver stiffness can be directly equated to liver fibrosis. New blood markers are also now available which can accurately estimate degrees of liver fibrosis and add to traditional methods of assessing for liver disease. No studies as of yet have been done in assessing the utility of the fibroscan(Transient Elastography) and serum fibrosis markers in a type 2 diabetic population.

Current practice is that once patients are discharged from hospital after surgery they do not have dietetic follow up. The aim of this study is to investigate whether individualised nutrition counselling improves nutritional status and quality of life in the 6 months post-discharge.