ANZCTR search results

Chronic Obstructive Pulmonary Disease (COPD) is a major contributor to the burden of disease in Australia. Increasing prevalence of chronic diseases has seen a shift in patient care paradigms towards disease specific programmes that focus on self-management. This new model for COPD care involving mentoring by trained nurses to increase self-efficacy aims to improve the health-related quality of life of people with COPD, while reducing associated healthcare costs through the early identification and treatment of acute exacerbations. Research Plan: A randomised study of participants with COPD recruited from general practices compares the model with usual care. Participants recruited to the active arm will have an individual management plan developed by the research team in consultation with their general practitioner. Nurses, trained in methods to improve self-efficacy, will work in partnership with participants to achieve behavioural change through a cycle of goal setting and action planning, focussing on health behaviours identified in the management plan. Outcomes will include health-related quality of life, self-efficacy, healthcare utilisation, lung function and physical activity.

This study will monitor whether you develop tearing and if so, how frequent and severe this complaint is. It will involve assessment of theeyes before start chemotherapy, during and at the end of treatment.

This 12month low intensity, randomised controlled intervention is delivered in conjunction with primary schools. It builds on the exisiting community efforts to control the prevalence of obesity and related disorders. It addresses barriers to attendance and is low cost and adaptable to communities

The aim of this trial is to estimate the difference in pain associated with the wearing or removal of suction or non-suction drains following gynaecological laparoscopic surgery.

'Repeat percutaneous facet joint denervation for chronic back pain: a prospective study for improvement in low back outcome score - this study will involve between 65-75 participants who have had an initially successful facet joint denervation and will follow them prospectively as to the success, as judged by the LBOS, with their repeat procedure.

To evaluate the exercise capacity of patients implanted with a VENTRASSIST® left ventricular assist device

AIM: To determine the impact of mechanical bowel preparation on patient symptomatology and surgical field in deep pelvic gynaecological laparoscopic surgery. HYPOTHESIS: That there is no difference in patient comfort or the surgical field when patients have mechanical bowel preparation by fasting alone, minimal residue diet alone or minimal residue diet with osmotic mechanical bowel preparation prior to advanced laparoscopic gynaecological procedures involving the posterior compartment BACKGROUND: For advanced gynaecological procedures involving the posterior compartment, there is, as yet no evidence to support or refute the use of mechanical bowel preparation, despite its widespread use in clinical practice. Only one study has assessed the impact of mechanical bowel preparation prior to gynaecological laparoscopic surgery, demonstrating increased patient preoperative discomfort with bowel preparation (1) 1. Muzii L, Bellati F, Zullo MA, Manci N, Angioli R, Panici PB. Mechanical bowel preparation before gynecologic laparoscopy: a randomized, single-blind, controlled trial. Fertility and Sterility 2006 Mar;85(3):689-93.

This study sought to determine the efficacy of universal web-based screening and provision of motivational feedback to reduce hazardous drinking among a university undergraduate student population.

The study aims to compare 2 commonly used modes of ventilation in patients with respiratory failure from neuromuscular disease or chest wall disease such as kyphoscoliosis. The study population will be patients already on mechanical ventilation to assist their breathing. As there is no current evidence that one treatment is better than the other, we wish to study the 2 ventilation modes in a crossover design (i.e. one treatment will be followed by the other on each patient) with regards to efficacy of ventilation and sleep quality on each mode. The study hypothesis is that there is no difference between the 2 modes (called the null hypothesis). The study will then attempt to prove whether this is true (i.e. accept the null hypothesis meaning that there is no difference), or false (i.e. reject the null hypothesis meaning that there is a difference between the 2 modes ). The study will help in the long term to determine which mode is more efficacious and comfortable to the patients with neuromuscular or chest wall disease.