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Rib fractures are a common injury. They can cause significant pain and lead to serious complications including death. Pain can affect the recovery from rib fracture, in particular how quickly a patient gets back to work or their activities of daily living. The aim of this study is to test the hypothesis that the operative management of patients with displaced (severe) rib fractures, via fixation of the fractures with an absorbable mesh plate, i) decreases the complications patients suffer from these injuries while in hospital, and ii) improves pain so that they can get back to work and normal activities quicker, and with an improved quality of life.

Dendritic cells will be grown from metastatic melanoma patients' peripheral blood and used to present common tumour antigens (peptides) or tumour extracts as a vaccine. In addition, some patients will receive low dose IL-2 in addition to their vaccine. IL-2 has been shown to increase the life of cytotoxic lymphocytes generated in animal and human vaccines.

No studies to our knowledge have been published on the use of aquatic physiotherapy from Day 4 post-operatively after THR or TKR surgery. This randomised controlled trial was therefore undertaken to investigate whether inpatient aquatic physiotherapy from Day 4 in addition to usual ward physiotherapy improved early functional recovery more than non-specific water exercise or additional ward physiotherapy. The primary endpoint of the trial was Day 14. Considering the usual level of activity in healthy older people, rehabilitation to optimal function after joint replacement is usually the aim of physiotherapy. Reduced strength and gait dysfunction can persist for many months after joint replacement. If return to normal function and activity is the goal of physiotherapy intervention after joint replacement surgery, follow-up beyond the early post-acute phase is important to understand the longer term impact of early rehabilitation. Participants were therefore followed up for six months after surgery to more thoroughly gauge functional recovery.

Observation of difference in insertion time, complications and patient satisfaction of Peripheral inserted central catheters with and without ultrasound

The Timed Up and Go (TUG) test is a test for measuring functional mobility and falls. It is quick, easy to perform and reliable in a clinic setting. Rehabilitation in the Home (RITH) physiotherapists utilise the TUG test to assess and reassess clients in their home environment. However, there is no data on the reliability of TUG in the home environment. It is also difficult to complete the test with the recommended seat height in the home environment. This study aims to investigate the reliability of the TUG in the home environment, compared to the outpatient setting and to determine the reliability of the TUG when a non-standard chair is utilised for the testing.

Study in healthy adult subjects of an antigen-sparing influenza vaccine strategy incorporating an immune enhancing polysaccharide in the normal influenza vaccine

To provide a structured and specialized Survivorship Clinic for 5-year plus survivors of Hodgkin's Lymphoma who were originally treated in The Queen Elizabeth Hospital and The Royal Adelaide Hospital in South Australia. The purpose is to reduce the severity of 'late effects' resulting from the curative treatment these survivors received by early detection of problems.

In this study, we aim to improve the evidence-based management of moderate to severe COPD patients with concurrent obstructive sleep apnea. Our primary hypothesis: Treatment of moderate to severe OSA with CPAP in patients with GOLD Stage III COPD leads to reduced systemic inflammation. Our secondary hypotheses: 1. This reduction in inflammation is associated with an improvement in respiratory outcomes (Quality of life, symptoms) in COPD. 2. CPAP therapy is well-tolerated in COPD patients with significant OSA.

This study will assess how a sample group of approximately 3000 angina patients are being managed in Australia.