ANZCTR search results

In a multicentre prospective double-blinded randomized trial, we will compare 3 laparoscopic methods for the repair of large hiatus hernia a) Repair using either sutures alone b) Repair with Biomesh (absorbable) c) Repair with Timesh (non-absorbable). to determine: 1) Short term and long term effectiveness of the hernia repair 2) Risk of postoperative side effects This trial will test the hypothesis that there is no difference in the incidence of recurrent hiatus hernia for the 3 different techniques of repair of large hiatus hernia. The primary outcome will be the integrity of the hiatal repair assessed by barium meal X-ray. Secondary outcomes will include clinical recurrence of the hernia, the development of post-operative reflux, the development of post-operative side effects, and overall satisfaction with the surgical outcome.

Our specific aim is to examine the effect of health worker education intervention on asthma outcomes using a randomised controlled trial. All children involved in the study will receive routine culturally appropriate intervention and thus the community will benefit in general. Additional asthma education by health workers using education material specially developed for the region can directly and indirectly improve the care of children with asthma ultimately with better asthma outcomes. Assuming the study hypothesis is correct, that children who receive additional asthma education by health worker have better asthma outcomes, the possible beneficial outcomes (educational interventions for improved asthma control) of this study can significantly affect rural communities at the regional and potentially national levels. In addition, a culturally appropriate method to reinforce asthma education could be used in the wider Indigenous community to improve asthma outcomes.