ANZCTR search results

This trial aims to assess the efficacy of antibiotics in treating children with a prolonged wet cough.

Raloxifene is a member of a family of compounds called selective estrogen receptor modulators (SERMS) that exert many of the beneficial effects of estrogen replacement without the associated increase in risk of breast and uterine cancer. Growth hormone (GH) replacement is beneficial in adults with hypopituitarism. Most GH deficient women also require oestrogen replacement. Oral oestrogens antagonise GH action at the liver, thereby reducing its beneficial effects on body composition and metabolism. The aim of this study is to investigate whether SERMs exert less of a negative influence on the effects of GH replacement, and therefore would be superior to conventional estrogen replacement in this setting.

This project aims to apply evidence based health promotion strategies to people with chronic or recurring mental disorders (CRMD) in an attempt to reduce physical risks. Conducted across three streams, intervention trials will focus on (i) People in urban areas or regional centres who require high levels of support to improve outcomes for those in need high support; (ii) patients of primary care practitioners and mental health services in rural towns and regional centres. The rural stream aims to detect and prevent relapse in mental disorders; reduce risk of physical disorders associated with smoking, excessive alcohol use, unhealthy diet and low activity levels. (iii) Indigenous consumers of mental health services in remote areas and examines contrasting models of mental health services and related information systems. The approach incorporates principles and priorities of the 2nd National Mental Health Plan and attempts to increase the capacity of stakeholders to manage CRMD. It is designed to be sustainable and widely applicable. Overall the study seeks to develop and demonstrate sustainable methods of improving mental health outcomes. Strategic priorities include: enhanced responsiveness of practitioners and service systems to the health risks faced by people with chronic or recurring mental disorders.