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Effects of circadian disruption and sleep deprivation in respiratory disorders
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Effects of circadian disruption and sleep deprivation in respiratory disorders
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SIMPLE LIFESTYLE STRATEGIES TO TREAT OBSTRUCTIVE SLEEP APNOEA
Expand descriptionSubjects randomly allocated to receive either active, aggressive diet and exercise program or simple information sheet only, for 4 months
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EVALUATION OF THE UTILITY AND COST OF A HOME-BASED PORTABLE POLYSOMNOGRAPHY SYSTEM.
Expand descriptionSleep studies on 4 consecutive nights, 2 in-lab, 2 at-home, in random order
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THE INTERACTIONS BETWEEN SLEEP DISORDERED BREATHING, METABOLIC SYNDROME AND VASCULAR RISK
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INSTEP Trial
Expand descriptionFor pain relief after VATS pleurodesis, patients are given either Celebrex or Placebo for 5 days plus any other required analgesics. We aim to determine whether there is any difference in failure of the lung to adhere to the lining of the chest.
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HATS trial
Expand descriptionTo determine whether a new form of minimally invasive ("keyhole") surgery results in less pain and suffering than traditional surgery of the lung via thoracotomy.
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Passive joint mobilisation for the treatment of shoulder pain and stiffness
Expand description90 volunteers presenting for treatment at a public hospital outpatient department with restricted, painful shoulder dysfunction will be recruited. Following an initial examination to obtain baseline data subjects will be randomly allocated to one of two treatment groups: advice and exercises or advice, exercises and passive joint mobilisations. Subjects will attend between 4 and 8 treatment sessions over a one month period. Outcome measurements will then be re-assessed. Following re-assessment treatment may continue for a maximum of 10 treatment sessions over a maximum of 8 weeks. Re-assessment will be repeated 6 months after recruitment.
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Efficacy and safety of vertebroplasty for treatment of painful osteoporotic spinal fractures: a randomised double-blind placebo-controlled trial
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A randomized phase III study to evaluate the effects of Oxpentifyllene as an add on therapy for boys with duchenne muscular dystrophy in improving muscle strength and function.
Expand descriptionOxpentifylline is being trialled as an add on drug to steroids - at present the only known med to positively influence DMD. It is thought that it may reduce some of the secondary problems in muscles such as fibrosis and inflammation.