ANZCTR search results

The primary aims of this two-armed randomised controlled trial are to assess whether coaches who attended coach education sessions can increase their female athletes' moderate-to-vigorous physical activity and reduce their time spent inactive during training sessions over a 5-day basketball program; compared to a no-treatment control group. Therefore, we hypothesise that: 1) Girls who are being coached by coaches who have attended coach education sessions will spend a greater percentage of time moderately-to-vigorously physically active compared to girls who are coached by coaches who did not attend coach education sessions. 2) Girls who are being coached by coaches who have attended coach education sessions will spend a lower percentage of time inactive compared to girls who are coached by coaches who did not attend coach education sessions. The target population for this study will be girls aged 9-12 years willing to partake in a 5-day basketball camp; and coaches, with basketball coaching certification and experience coaching girls, willing to coach a 5-day basketball camp.

During the first few months of life, parent reported infant sleep and crying problems are common (20-40% and 20% of infants, respectively; Bayer et al, 2007; Wake et al, 2007), as well as costly to treat (Hiscock et al 2007). Six randomised controlled trials have shown that providing parents with information on normal infant sleep and crying, and strategies to encourage good sleep habits, can improve infant sleep as well as reduce maternal postnatal depression symptoms (Hiscock et al , in preparation). While there is evidence that such strategies are of significant benefit to families and are well accepted by families, dissemination of this information to all families with newborns will be challenging. Our research team, in consultation with other health care professionals, has developed Cry Baby – an interactive online program that draws on prior research findings to provide parents with evidence based strategies for how to cope with infant sleep and crying problems. The aim of this research is to: (1) trail two different recruitment processes for providing the Cry Baby program in order to determine the best way to ensure it effectively reaches the families who would benefit; (2) collect data on how families engage with the resource (i.e., when they access it, what they access, how useful they find it) to better refine the program; (3) collect data on whether email support increases program participation, and; (4) collect preliminary data on outcome measures. Parents will be recruited from two settings: (1) the Maternal and Child Health (MCH) service at the 2 week visit, and; (2) through advertisements on the Raising Children Network (RCN) website. Parents will be randomly assigned to either receive the Cry Baby program with email support from the research team, or to receive the Cry Baby program without additional email support. Data collected from this pilot study will indicate: (1) whether recruitment via online advertising (RCN) or via known health professional (MCH) result in a sample of participants more reflective of the general community (household income, education, socioeconomic status, language); (2) whether providing weekly email support results in parents (a) logging in to the program more often, (b) completing a greater proportion of the program, and (c) increased retention to the program; and (3) whether parents find the program useful/helpful.

To characterize the pharmacokinetics (PK) of esketamine hydrochloride from 2 oral and 1 sublingual formulations of IPX237 compared to that from intravenous esketamine hydrochloride.

The study aims to assess the effect of omalizumab (Xolair) on systemic and cutaneous mastocytosis

Carpal Tunnel Syndrome (CTS) is the most common condition affecting the upper limb and is associated with significant socioeconomic and quality of life costs. CTS is either treated conservatively (provision of wrists splints and exercises) or with surgery. However, long public health orthopedic waiting lists often mean symptoms have progressed beyond the point of conservative management being an option. The aim of this project is to implement a therapy based, screening and early intervention clinic for patients with CTS, to determine its effect on waiting lists, benefits to Hospital based health services and patient satisfaction and clinical outcomes. The participant group will be those who have been referred to QEII Hospital Orthopedic dept by their General Practitioner for management of CTS. The method will involve a standard care group who will receive the currently implemented management (i.e. staying on the orthopedic department waitlist for review), and the enhanced care group who will receive early intervention and conservative management. The standard care group will receive treatment at the conclusion of the study, which will still be sooner than they would otherwise normally receive it.

This paper reports on the post-transplant lymphoproliferative disease (PTLD) experience of a single centre heart and lung transplant unit from its inception in 1984 to 2011 with respect to patient demographics, risk factors, management and outcomes. This detailed retrospective analysis aims to identify risk factors and describe outcomes in heart and lung transplant patients with PTLD to understand the unique clinical features of their disease in order to further develop tailored treatment strategies and prophylaxis.

Transcranial direct current stimulation (tDCS) is a non-invasive brain stimulation technique with the potential to improve function and learning in neurological conditions. However, evidence in PD is limited to three small pilot studies, all of which use sub-optimal tDCS protocols. Here we aim to undertake a preliminary trial to investigate the effect of tDCS coupled with dual task training on gait disturbances in PD. In addition we will examine the effect of tDCS on bradykinesia, motor function and learning. This novel and innovative research has the potential to improve the function and quality of life for over 4 million individuals living with PD.

The purpose of this quality improvement project is to undertake a series of studies with the overall aim of increasing the frequency of mobilisation of patients in the Royal Adelaide Hospital Intensive Care Unit. The study will comprise four parts as follows: 1. A prospective audit of the frequency of mobilisation in the Royal Adelaide Hospital Intensive Care Unit, including reasons that patients are not mobilised. 2. A prospective survey evaluating Royal Adelaide Hospital Intensive Care Unit staff’s perceptions of the barriers to mobilising Royal Adelaide Hospital Intensive Care Unit patients. 3. Implementation of strategies to address these barriers (e.g. education, improving inter-disciplinary communication). 4. A prospective repeat audit of the frequency of mobilisation in the Royal Adelaide Hospital Intensive Care Unit following implementation of these strategies, including reasons that patients are not mobilised. THis registration form is for parts 1 and 4 of the study.

The purpose of this quality improvement project is to undertake a series of studies with the overall aim of increasing the frequency of mobilisation of patients in the Royal Adelaide Hospital Intensive Care Unit. The study will comprise four parts as follows: 1. A prospective audit of the frequency of mobilisation in the Royal Adelaide Hospital Intensive Care Unit, including reasons that patients are not mobilised. 2. A prospective survey evaluating Royal Adelaide Hospital Intensive Care Unit staff’s perceptions of the barriers to mobilising Royal Adelaide Hospital Intensive Care Unit patients. 3. Implementation of strategies to address these barriers (e.g. education, improving inter-disciplinary communication). 4. A prospective repeat audit of the frequency of mobilisation in the Royal Adelaide Hospital Intensive Care Unit following implementation of these strategies, including reasons that patients are not mobilised. This registration form is for part 2 of the study.

The primary purpose of this study is to compare the effectiveness of two exposure-led interventions on children's vegetable acceptance and intake. Low acceptance is one of the key reasons for low consumption of vegetable in children. A randomized controlled design study will compare two exposure-led interventions to a control group, in 4-6 year old children, whose parents would like their child to eat more vegetables. Both intervention groups will be exposed to small quantities of vegetables in the home environment. Effect on vegetable acceptance and dietary intake will be compared between groups, and with the control group, before and after an at home exposure intervention, as well as after a three month follow up. It is hypothesized that the interventions will lead to increased vegetable acceptance and intake in children.