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The purpose of this study is to compare hair drug analysis with urine and blood drug analysis which is currently used for investigating allegations of drug facilitated sexual assault (DFSA). Our hypothesis is that hair drug analysis will detect additional drugs than those detected in urine and blood samples. In addition, we hope to document drugs involved in suspicions of DFSA in the South Australian population, identify which drugs may have improved detection with hair toxicology and document time frames for drug detection in different biological specimens.

This study has been designed to investigate how the extent of hydrolysated protein effects gut motility, gut hormones and appetite sensations. Volunteers are required to visit the clinic on 3 occassions no less than 3 days apart. Visits will last for approximately 5 hours. A long flexible tube will be inserted through an anaesthetised nostril and passed through into the small intestine to monitor stomach and small intestinal contractions. Through this tube, a protein solution will be infused into the small intestine over a 90 minute period. Blood samples will be taken (through a cannula, which is a long flexible tube inserted into a vein) and questionnaires on appetite sensations will be completed every 15 minutes. At the end of the 90 minute solution infusion, a buffet meal will be provided. This meal will be consumed over 30 minutes until the volunteer is confortably full.

Neutropenia is a complex haematological disorder charactarised by a abnormally low level of neutrophils in the blood. F-627 is being developed to treat neutropenia especially for the management of neutropenia in patients with cancer. F-627 is being developed by Generon (Shanghai) Corporation to provide additional benefits to cancer patients by shortening the duration and lessening the severity of neutropenia after chemotherapy. The purpose of this study is to researech the safety of the use of F-627 in Healthy Male Volunteers. There will be no benefits from participating in this trial, Patients will receive only one dose of study drug.

Modern anaesthesia incorporates the use of short-acting opioids such as remifentanil. Lately, there has been emerging evidence in the literature that some opioids might influence postoperative sleep quality for up to many months. We aim to compare sleep quality after exposure to 2 opioids regularly used in the clinical routine at Royal Perth Hospital.

STRIVE – Sexually Transmitted infections in Remote communities: ImproVed and enhanced primary health care services is a new trial which aims to reduce levels of STIs in 21 or more participating ‘trial clusters’ over a five year period. STRIVE is 5 year project in partnership between the National Centre in HIV Epidemiology and Clinical Research, the Menzies School of Health Research and government and community organisations in NT, WA and QLD. Funding for the trial was awarded by the National Health and Medical Research Council (NHMRC Project Grant, Application ID: 568806, 2009-2013). Proposed clusters of communities will be located in the NT, WA and QLD. STRIVE will test whether the development and then implementation of a Sexual Health Quality Improvement Program tailored for primary health care centres will improve STI service delivery and assist these services on reaching best practice in STI control. STRIVE will also provide incentive payments for achieving aspects of best practice in STI care.

Weight loss and under-nutrition is common in older people and associated with poor outcomes. This includes increased rates of hospital admissions. In a pilot study of ndernourished older, community dwelling people we found that daily treatment for one year with a combination of testosterone tablets and a nutritional supplement produced a significant reduction in hospitalizations. We propose a larger, multicentre study to explore and hopefully confirm this exciting, potentially important finding.

Small amounts of sweet tasting sugar water reduces pain in babies during painful blood tests and injections. We do not know if sugar also reduces pain in toddlers and young children. This project will help to determine if small amounts of sugar water reduce pain in toddlers during their immunisations and venepuncture and if sucking on a lollypop helps to reduce pain in pre-school children between 3 and 5 years of age during their injections for immunisation. The immunisation part of this study will be done in the Royal Children’s Hospital Immunisation Centre where mothers and fathers bring their children in to have their scheduled childhood immunisations done. The part of the study examining sucrose efficacy in hospitalized toddlers during venepuncture will be conducted in Canada, at CHEO in a surgical ward.

This trial is a prospective evaluation of a new method of diagnosing coronary calcium, using standard non contrast calcium score as the reference standard.

Acromioclavicular (AC) joint pathology is a common cause of shoulder pain. The location of pain originating from the AC joint can be diverse and patients are often not able to identify the exact location. In most patients the pain will be located in an area bounded by the mid-part of the clavicle and the deltoid insertion, but the pain has also been shown to radiate to the radial side of the forearm into the thumb. AC joint pathology can occur in isolation, but is often associated with other causes of shoulder pain, such as subacromial impingement or rotator cuff pathology. Surgical treatment of other causes of shoulder pain can affect the AC joint, and arthroscopic acromioplasty may have detrimental effects on an already compromised AC joint. Conversely, residual AC joint pathology has been shown to have a negative effect on the outcome of surgery to the rotator cuff. Detection of AC joint pathology is therefore crucial in the treatment of patients with any type of shoulder problem and various clinical tests have been described to asses AC joint pathology. The primary aim of this study was to assess the diagnostic sensitivity of the BvR (Bell-van Riet) test, when compared with other tests.

To investigate whether supplementation with combined fish oil/CoQ10 alters hepatic triglyceride concentration, composition and cardiovascular risk factors in overweight men.