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In a previous study on bronchiolitis in Aboriginal children we found that 67% were from remote communties and required retrievals. A recent study has also shown that almost 2.5% of Aboriginal children in Australia's Northern Territory will be hospitalised for bronchiolitis more than once before reaching the age of 18 months. Multiple hospitalised respiratory infections and the severity of these infections are risk factors for developing chronic lung diseases including bronchiectisis and asthma. It is planned that this study will provide an estimation of the effect of azithromycin on the severity of bronchiolitis in Aboriginal and non Aboriginal infants. Assessing redmission for respiratory illness within 6 months may provide some indication of the medium term benefit of a single dose of azithromycin, given to infants in the acute phase of viral bronchiolitis, in reducing the risk of further respiratory illness requiring hospitalisation.

This study proposes to evaluate the efficacy and safety of ear-acupressure in the treatment of adult patients with allergic rhinitis by conducting a multi-centre, randomised, sham-controlled clinical trial. A pilot study will be conducted in Australia prior to the main trial.

The primary objective is to evaluate the safety and tolerability of subcutaneous injections of ART621 given every 2 weeks for 6 doses as assessed by adverse events and clinical laboratory data. Assessments of efficacy will include the Psoriasis Area and Severity Index (PASI), Physician Global Assessment (PGA), photographs and the Dermatology Life Quality Index (DLQI). Each subject will be on-study for 18-20 weeks, consisting of a 2-4 week screening period, followed by a 12 week treatment period and then a 4 week follow up. Each subject will receive their designated dose of ART621 on 6 occasions over the 12 week treatment period and will be monitored closely throughout.

Exercise training improved short-term and long-term exercise capacity and health-related quality of life compared to no exercise training in people with dust-related respiratory diseases.

Caesarean section is a common operation and for different parts of the operation techniques vary widely between surgeons. Information is lacking about the best techniques and how different techniques may affect the mother's health. We propose to evaluate two methods of stitching up or closing the skin and whether to close or not to close the fatty layer beneath the skin. We want to know if these different methods cause differences in wound problems after birth and also whether there is a difference in pain and the mothers general physical and emotional health. We aim to examine these methods in approximately 700 women over a 2 year period and will follow them until 6 weeks after the birth.

This study examines the effects of different colours of light on sleepiness and performance on various tasks. It is predicted that exposure to blue light will reduce sleepiness and improve performance more effectively than other colours of light.

The primary purpose of the study is to determine whether women prescibed a twelve month supply rather than the usual four month supply of the combined oral contraceptive pill at initiation of this contraceptive method are more likley to continue this method when followed-up by phone or e-mail twelve months later. The study will also look at womens' preferences for each initiation regimen through administration of a questionnaire. The hypothesis is that women are more likley to continue the contraceptive pill if they are prescribed the longer initiation regimen and will have a preference for this regimen over the shorter four month regimen.

This is a multi-center, randomized, parallel-group, open-label, 2 treatment group study to evaluate the safety and efficacy of Fluticasone Proprionate Nasal Drops, Nasal Spray and Suspension for Nebulization via Nasal Inhalation for the treatment of chronic sinusitis in post-surgical subjects 18 years of age and older.

The Cambridge Pulmonary Hypertension Outcome Review (CAMPHOR) is the only available questionnaire specifically developed for patients with pulmonary arterial hypertension (PAH). The CAMPHOR has been used in the United Kingdom to measure quality of life (QoL) in patients with PAH. This study aims to investigate whether the CAMPHOR is a useful questionnaire for an Australian and New Zealand group of patients with PAH, as well as to see whether it more accurately reflects changes in QoL in this group when compared to a widely used generic QoL questionnaire (the Short Form 36). Measuring QoL is important outcome measure to determine the effectiveness of treatment from the patient’s perspective.