ANZCTR search results

The aim of this trial is to estimate the difference in pain associated with the wearing or removal of suction or non-suction drains following gynaecological laparoscopic surgery.

'Repeat percutaneous facet joint denervation for chronic back pain: a prospective study for improvement in low back outcome score - this study will involve between 65-75 participants who have had an initially successful facet joint denervation and will follow them prospectively as to the success, as judged by the LBOS, with their repeat procedure.

To evaluate the exercise capacity of patients implanted with a VENTRASSIST® left ventricular assist device

AIM: To determine the impact of mechanical bowel preparation on patient symptomatology and surgical field in deep pelvic gynaecological laparoscopic surgery. HYPOTHESIS: That there is no difference in patient comfort or the surgical field when patients have mechanical bowel preparation by fasting alone, minimal residue diet alone or minimal residue diet with osmotic mechanical bowel preparation prior to advanced laparoscopic gynaecological procedures involving the posterior compartment BACKGROUND: For advanced gynaecological procedures involving the posterior compartment, there is, as yet no evidence to support or refute the use of mechanical bowel preparation, despite its widespread use in clinical practice. Only one study has assessed the impact of mechanical bowel preparation prior to gynaecological laparoscopic surgery, demonstrating increased patient preoperative discomfort with bowel preparation (1) 1. Muzii L, Bellati F, Zullo MA, Manci N, Angioli R, Panici PB. Mechanical bowel preparation before gynecologic laparoscopy: a randomized, single-blind, controlled trial. Fertility and Sterility 2006 Mar;85(3):689-93.

This study sought to determine the efficacy of universal web-based screening and provision of motivational feedback to reduce hazardous drinking among a university undergraduate student population.

The study aims to compare 2 commonly used modes of ventilation in patients with respiratory failure from neuromuscular disease or chest wall disease such as kyphoscoliosis. The study population will be patients already on mechanical ventilation to assist their breathing. As there is no current evidence that one treatment is better than the other, we wish to study the 2 ventilation modes in a crossover design (i.e. one treatment will be followed by the other on each patient) with regards to efficacy of ventilation and sleep quality on each mode. The study hypothesis is that there is no difference between the 2 modes (called the null hypothesis). The study will then attempt to prove whether this is true (i.e. accept the null hypothesis meaning that there is no difference), or false (i.e. reject the null hypothesis meaning that there is a difference between the 2 modes ). The study will help in the long term to determine which mode is more efficacious and comfortable to the patients with neuromuscular or chest wall disease.

To find out the efficacy of vaginal vault prolapse repair with uterosacral ligament suspension via vaginal approach to those of the current gold standard surgery of sacrocolpopexy

Failure to immobilise the neck during tracheal intubation in patients with cervical spine injuries (CSI) can result in a devastating neurologic outcome. One method to immobilise the neck during laryngoscopy and tracheal intubation is manual in-line neck stabilisation (MILNS). With MILNS, however, it is often more difficult to visualise the larynx using conventional laryngoscopy. Consequently, the application of MILNS may result in failure to secure the airway, which may result in substantial morbidity or even mortality. These issues highlight the need to develop alternative approaches to securing the airway in patients with CSI. The purpose of the proposed study is to compare the performance of the Airway Scope and GlideScope laryngoscopes for tracheal intubation in patients with cervical spine immobilisation using MILNS. The GlideScope laryngoscope, is a modification of the standard Macintosh blade, with a high-resolution camera and with a light source for illumination embedded within the blade. Endotracheal intubation is performed based on an image on a screen. Its use is well described in the airway management of patients with immobilised cervical spines. The Airway Scope, in contrast, is a novel intubation device. It is a video laryngoscope with a reusable handle and desposible blade. A number of design features that suggest its utility in the setting of cervical spine immobilisation. A limited amount of research to date has generally supported this proposition. We intend to conducting a randomised, single-blind, controlled clinical trial. All patients will receive a standardised general anaesthetic with routine non-invasive monitoring. The neck will be immobilised using MILNS applied by an experienced assistant. Participants will be randomly assigned to tracheal intubation with either the Airway Scope or the GlideScope. All intubations will be performed by one anaesthetist experienced in the use of both laryngoscopes. The primary outcome measures will be intubation time and the Intubation Difficulty Scale score. Any complications or difficulties will be recorded.

The aim of the study is to to determine whether land- or water-based rehabilitation is the more effective mode of delivery following primary total knee replacement (TKR) in the sub-acute period.