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Prevalence and predictors of malnutrition and decreased bone density in cystic fibrosis
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VMCL Melanoma Vaccine Treatment Phase II Study for Therapy of Patients with Advanced Stage IV Melanoma
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Dendritic cell vaccination trial for hormone refractory prostate cancer with autologous tumour as the antigen
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Phase I trial of the safety and the effect on immune parameters of an immunotherapy for glioma based on cultured autologous dendritic cells presenting autologous tumour cell antigens derived from irradiated glioma cells
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Effect of exercise on mucus rheology and inspiratory/expiratory flow-volume relationships in people with Cystic Fibrosis
Expand descriptionThe trial completed recruitment and data collection in 2007. Manuscript was published in Chest 2011, vol 139(4):870-877.
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Measurement of environmental factors in asthma control
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Randomised 12 month trial of Non-Invasive Ventilation (NIV) with or without oxygen versus oxygen alone in treatment of sleep disordered breathing in Cystic Fibrosis
Expand descriptionLast participant recruited 16/4/2010. Recruitment halted 2015 as no participant recruited in last 5 years. Data analysis ongoing.
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IBCSG 26-02 / BIG 4-02: Premenopausal Endocrine Responsive Chemotherapy Trial
Expand descriptionEstrogen can stimulate the growth of breast tumor cells. Suppression of ovarian function combined with hormone therapy may fight breast cancer by reducing the production of estrogen. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. It is not yet known whether suppression of ovarian function and hormone therapy are more effective with or without chemotherapy in treating breast cancer. This randomized phase III trial is studying how well giving ovarian-function suppression together with hormone therapy and chemotherapy works compared to ovarian-function suppression and hormone therapy alone in treating premenopausal women with resected breast cancer.
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IBCSG 25-02 / BIG 3-02: Tamoxifen and Exemestane Trial
Expand descriptionResearch has shown that exemestane works better in postmenopausal women because their ovaries are no longer producing oestrogen. TEXT will determine if suppressing ovarian function in premenopausal women (i.e. reducing oestrogen production) will allow exemestane to work in the same way as it does for postmeopausal women. This trial is designed for participants who should receive ovarian function suppression from the start of their adjuvant breast cancer treatment.
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A prospective randomised study comparing two techniques for establishing Continuous Femoral Nerve Blockade for postoperative analgesia following Total Knee Joint Replacement
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