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Pre-hospital rapid sequence intubation in patients with severe head injury
Expand descriptionThis study will determine whether paramedic intubation at the scene improves outcomes compared with intubation at the hospital in patients with severe head injury
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INFLAMMATION and VASCULAR FUNCTION in ACUTE STROKE and TIA: TREATMENT WITH ATORVASTATIN and IRBESARTAN
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Anti-inflammatory effects of pioglitazone in acute stroke - a double-blind placebo controlled trial
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Prosthetic evaluation program
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Comparing two treatmetns for ulcerated hemagiomas.
Expand descriptionPending
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A prospective study of the effects of weight loss on knee pain, function and appearance on x-ray in severely obese women.
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Acute Stroke Treatment with Atorvastatin and Irbesartan
Expand descriptionThe study aims to examine the effect of early treatment of acute ischaemic stroke with an ATRA and statin on surrogate markers of clinical outcome comprising the local response to ischaemia, cerebral blood flow, infarct growth and recurrent cardiovascular events.
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A randomised pilot study to investigate the optimum timing of gemcitabine and concurrent radiation therapy after induction gemcitabine and carboplatin for locally advanced non-small cell lung cancer
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A double blind randomised placebo-controlled intervention trial to determine the efficacy of the probiotic VSL #3 in reducing the incidence and or frequency of diarrhoea in enterally-fed critically ill patients.
Expand descriptionIt is not clearly understood why some critically ill patients develop diarrhoea while being fed by stomach tube. Diarrhoeal illness has been linked to infection and treatment by antibiotics which can disrupt the normal functioning of the gastrointestinal tract. Excessive diarrhoea may cause patients not to digest the essential nutrients they need to overcome illness. Severe cases of diarrhoea may also lead to discomfort and loss of dignity for the patient. Health professionals continually seek new therapies to remedy the onset of diarrhoea and the potential discomforts associated with it. The aim of this study is to find out whether commercially available probiotic preparations (like yoghurt type foods) have the ability to reduce the frequency of diarrhoea in patients receiving their nourishment by feed tube in the intensive care unit. A secondary aim of this study is to find out whether probiotic preparations can decrease infection rates in seriously ill patients. Probiotics are not drugs and through out the world they are considered to be very safe. They represent a range of food ingredients or supplements which can be bought from health food shops and supermarkets. These foods contain live microbes many of which normally reside in the intestines. Research suggests that these foods improve intestinal health by restoring the normal balance of microbes in the gastrointestinal tract.
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Testing a home based rehabilitation program for survivors of a critical illness: a randomised controlled trial
Expand descriptionPeople who survive a critical illness often take a significant time to recover, and may not return to pre-illness levels of activity and function. This study will test whether an 8-week home based physical exercise program will provide any benefits to participants receiving the program, compared to participants not receiving the treatment. All participants will be assessed at weeks 1, 8 and 26 post-hospital discharge. Participants randomised to receive the exercise program will be visited at home by a trainer on 3 occasions in the 8-week period.