ANZCTR search results

The project aims to investigate in a sample of people with chronic obstructive pulmonary disease the effects of a psychological intervention as compared to a pulmonary rehabilitation program and then; compare six weeks of rehabilitation with and without weekly maintenance and construct a model to identify candidates who benefit most from maintenance. The incremental cost effectiveness of the three interventions will then be evaluated.

The project received ethical approval from the Children's Hospital at Westmead Ethics Committee,

This phase II study plans to trial monthly zoledronic acid therapy in patients with PET-detected bone metastases from non-small cell lung cancer, to assess whether zoledronic acid therapy has anti-tumour effects on subsequent PET scans, delays complications related to bony metastases, or is associated with a prolongation of overall or progression-free survival. We plan to study this question in patients with metastatic disease not being immediately commenced on palliative chemotherapy.

The overall aim of the CASA study is to investigate the role of PLD as adjuvant chemotherapy for older postmenopausal women for whom chemotherapy is indicated, but standard regimens, derived from trials in younger women, are assumed to be too toxic or inconvenient.

The aim of this study is to determine whether an oral vaccine against non-typeable Haemophilus influenzae will reduce the number of episodes of acute bronchitis experienced by people with mild to moderate airway disease.

The trial is evaluating whether the LHRH analogue goserelin, which temporarily suppresses ovarian function, can prevent permanent ovarian failure after chemotherapy in premenopausal women with hormone receptor-negative breast cancer.

This aim of this study is to determine whether an oral vaccine against non-typeable Haemophilus influenzae will reduce the number of episodes of acute bronchitis experienced by people with moderate to severe airway disease

Introduction/your consent You are invited to take part in this research project because you have pain related to cancer that requires radiotherapy. This research project is testing a new way of controlling pain especially during movement. The current standard treatment for movement pain includes morphine which is often not effective. This Participant Information Sheet tells you about the research project. It explains what is involved. This will help you decide if you want to take part in the research. Please read this Participant Information Sheet carefully. Ask questions about anything that you don’t understand or want to know more about. Before deciding whether or not to take part, you might want to talk about it with a relative, friend or your local doctor. If you decide you want to take part in the research project, then you will be asked to sign the Consent Form. By signing it you are telling us that you: · Understand what you have read in the information sheet · Consent to taking part in the research project · Consent to the use of your personal and health information as described in the information sheet. You will be given a copy of this Participant Information Sheet and Consent Form to keep as a record. Purpose and Background Doctors are looking for better ways to treat pain caused by movement especially when being transported to and from the radiotherapy department as an inpatient. In this research project, the researchers will test whether giving the medication, methoxyflurane given by inhalation (through a device called a Penthrox Inhaler), is better than the current standard treatment. The standard treatment is an extra dose of morphine, or similar medication, given half an hour before being moved to the radiotherapy department. No study has been done comparing the two treatments. Methoxyflurane has been approved for use in Australia to relieve acute pain. It is used in many situations including ambulances, emergency departments, dentistry, obstetrics and in children. It provides effective pain relief with very few side effects. Therefore this is not an experimental drug.

The aim of this trial is to improve communication of information provided to patients with rheumatoid arthritis who are starting treatment with methotrexate. All outcomes will be measured by a blinded assessor (not the treating rheumatologist). The patients will also be blinded in that they will not be aware of the trial at the time that they receive the educational intervention and will not be informed that their knowledge will be tested until they attend for the 6 week review at which time the patient knowledge questionnaire will be administered under supervision.