ANZCTR search results

This is an RCT to determine the effects of progressive resistance training during hemodialysis in patients with end-stage renal disease

This will be a single arm, multicentre study involving women diagnosed with non-metastatic locally advanced breast cancer. The study will assess the feasibility of developing a uniform approach with chemotherapy, surgery and radiation therapy in the treatment of locally advanced breast cancer. It will also define the rates of objective clinical response and complete pathological response following 6 cycles TAC. Further, the accuracy of breast MRI and PET in predicting extent of breast cancer in the pathological examination of the surgical specimen will be assessed.

Two monitoring devices (Skin conductance and bispectral index) are tested regarding their predictive value and reaction times for postoperative awaking.

To investigate the optimal training intensity for the improvement of muscle power during high velocity resistance training in older men and women

Nocturnal ventilatory support in obesity hypoventilation syndrome study has been completed now

Improvements in treatment results for adult acute myeloid leukaemia (AML) over the past 15 years have come mainly from the use of higher dose intensity of existing chemotherapy agents, rather than from the introduction of new classes of anti-leukaemic drugs. Increased dose intensity protocols have included the use of chemo-radiotherapy, Early intensification of treatment using the most effective drugs available for AML is a highly effective strategy, possibly through rapid elimination of potentially drug-resistant cells. Hypothesis; a) That Palifermin, given as three doses of 60 µg/kg per day IV before and three doses after ICE chemotherapy, will reduce the incidence of grades 3 and 4 oral mucositis. b) That an increase in the dose intensity of Idarubicin given early during the initial treatment of AML will result in significantly greater anti-leukaemic activity, and that this dose escalation of Idarubicin in consolidation treatment following induction therapy with high dose Cytarabine will achieve improved leukaemia-free survival.

The proposed research project will investigate whether high-intensity, community-based exercise programs performed once a week are sufficient to maintain or improve a variety of subjective and objective outcomes including the physical function, balance, independence and program adherence of older adults post-discharge from a Day Rehabilitation Centre (DRC). The â¿¿once a weekâ¿¿ exercise intervention will be directly compared with â¿¿twice a weekâ¿¿ exercise, and with usual care for a period of 12 weeks post discharge. Participants will be followed up at the end of the intervention period and at 12 months post discharge from the DRC. The cost effectiveness of the interventions will also be determined.