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Determination of the aspects of driving that occupational therapists believe are amenable to rehabilitation in the form of driving lessons
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Validation of a driving efficacy scale
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Rehabilitation and driving with Multiple Sclerosis
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A comparison of efficacy and tolerability using two portable sleep apnoea monitoring devices: nocturnal oximetry versus nasal airflow in the triage diagnosis and screening of obstructive sleep apnoea.
Expand descriptionObstructive Sleep Apnea (OSA) is a common disorder. It is linked to heart disease, stroke high blood pressure and poor cognition as well as motor vehicle and work accidents. However till now the diagnostic gold standard is in hospital overnight sleep study. This is expensive time consuming and has limited availability. Studies investigating the use of simple single channel monitors for OSA detection at home have predominantly involved device that measure oxygen in the blood (oximeters) with limited data available for devices that measure breathing (nasal flow). Our aim was to assess and compare the validity of nasal flow and oximetry recordings using separate single channel monitors in the laboratory on the same night as the sleep study and at home for a single and three nights each with respect to the laboratory sleep study.
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Randomised Phase II trial of irinotecan with hyaluronic acid (HyCAMP) versus irinotecan as treatment for patients with metastatic colorectal cancer who have failed 5-FU based chemotherapy
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Predictive value and reaction times of skin conductivity versus bispectral index for assessment of awakening after total intravenous anaesthesia
Expand descriptionComparison of skin conductance and bispectral index monitoring for prediction of postoperative awaking.
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Endoluminal Aneurysm Repair Surveillance
Expand descriptionEndoluminal repair of abdominal aortic aneurysm (enlargement of the main artery) is a relatively new procedure whic requires long term follow-up. This is usually done with computed tomography which has the disadvantages of repeated dose of contrast agents and radiation. We believe ultrasound can be used to follow-up patients after endoluminal repair with out any harmful effects.
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The effect of progressive resistance training on knee articular cartilage morphology in osteoarthritic patients
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A randomised phase II study to evaluate the effectiveness of botulinum toxin to delay, and possibly prevent, progressive foot deformities in children with Charcot-Marie-Tooth (CMT) disease.
Expand descriptionThis is a trial of a new therapy (botulinum toxin) for CMT to see if it will help to minimise or delay foot deformity in children with CMT.
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Hypofractionated radiotherapy for the palliation of patients with advanced head and neck cancer who are unsuitable for an attempt at curative treatment
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