ANZCTR search results

The study aimed to compare changes in various blood and urine markers of bone metabolism and inflammation in post-menopausal women drinking magnesium bicarbonate supplemented spring water or spring water without supplements. Additionally, the following other factors were investigated for change between treatment groups and general safety 1.venous blood pH 2.urine pH 3.blood pressure 4.serum lipids 5.serum biochemistry 6.haematology 7.urinalysis

Failure to attend appointments is a problem for health services. A high proportion of patients who do not attend (DNA) means that clinical and administrative staff are not efficiently employed, and results in longer waiting times for other patients that may increase the risk of further health problems. A recent audit of Eastern Health physiotherapy outpatient clinics found a DNA rate of 8.1%, representing more than 125 missed appointments per month. A review of the literature indicates providing reminders can be an effective method of reducing DNA rates for health services, and a couple of recent observational studies have provided preliminary evidence that sending patients reminders via the short message service (SMS) on mobile phones can be an effective way of reducing DNA rates. Therefore, the aim of this trial is to find out if sending SMS reminders to patients with appointments at physiotherapy outpatient clinics is an effective way of reducing DNA rates. Using a randomised controlled trial at 4 Eastern Health physiotherapy outpatient clinics, patients will be randomly allocated either to the group that will receive an SMS reminder or the group that receives usual care. The primary outcome is DNA rate, and secondary outcomes are cancellation rates and an initial estimation of costs in implementing the SMS reminder system.

Several randomized controlled trials have been conducted in preterm infants to determine whether inhaled nitric oxide (iNO) reduces the rates of death and/or chronic lung disease. The results of these studies appear contradictory. Some studies have shown a reduction in lung injury, one has shown a reduction in cerebral injury, and several others have shown no effect. The different patient characteristics and different trial characteristics within these trials may explain this difference. The purpose of this systematic review and individual patient data meta-analysis is to determine whether inhaled nitric oxide in preterm infants receiving assisted ventilation improves survival without morbidity, specifically without chronic lung disease (CLD), cerebral injury, retinal injury, and improves survival without long-term disability. Secondly to determine whether the effects of inhaled nitric oxide differ according to the risk profile of the patient in terms of gestational age at birth, severity of illness, antenatal steroid use, postnatal age at the time of randomization, ventilation mode at randomization, administration of exogenous surfactant, inhaled nitric dosage and duration of nitric oxide administration.

We aim to conduct a randomised controlled trial to determine the efficacy of two oral regimens of trimethoprim-sulfamethoxazole compared to benzathine penicillin (BPG), for the treatment of skin sores (also known as impetigo) in Aboriginal children living in remote communities. Trimethoprim-sulfamethoxazole may be a much more acceptable oral alternative compared to the uncomfortable and poorly received intramuscular benzathine penicillin which is the current standard of care.

This study aims to examine the effectiveness of a therapist assisted CD-ROM based intervention for children and adolescents with aggressive behaviour, and compare it to treatment as usual. The CD-ROM called “Face Your Problems” is already developed and in occasional use. The participants will be 60 children between the ages of 7 and 14 years who present to Mater Child and Youth Mental Health and Child and Youth Mental Health, Children's Health Service District, Queensland Health community clinics for the treatment of aggressive behaviours. Treatment will last between 10-13 sessions and consist of teaching strategies to reduce anger and come up with better solutions to problematic social situations.

The purpose of this study is to test the effectiveness of a new web-based treatment for cannabis use. The research hypothesis predicts that, relative to a placebo control group, individuals who receive the intervention will report greater reductions in their cannabis use, and in symptoms of cannabis abuse and dependence.

It is well established that parents of primary school aged children substantially influence the food and physical activity home environment through behaviours, attitudes, feeding styles and role modelling. However, the contribution of fathers’ influence on children’s physical activity and eating behaviour is often overlooked.The ‘Healthy Dads, Healthy Kids’ (HDHK) program was designed to engage overweight fathers to role model and promote positive behaviours relating to physical activity and healthy eating. Major aims of HDHK were (i) to help overweight/obese fathers achieve a healthy weight, and (ii) to improve the activity and eating behaviours of their children (using fathers as the key agents of behaviour change).

The purpose of this study is an attempt at treating neonates born with Molybdenum Cofactor Deficiency Type A. This study is a multi-site study open to participants living in ANY country WORLDWIDE, it is not restricted to the countries listed above.

Alpha-tocopherol plays an important role in preserving skin barrier function; it is concentrated in sebum and secreted to the skin in high concentrations. It is not known whether supplemented tocopheryl phosphates, which have been shown to play a protective role in prevention of UV damage, follow a similar metabolic pathway to the skin surface as alpha-tocopherol.

The purpose of this study is to understand how well Oxycodone in combination with tocopheryl phosphate mix (TPM), is absorbed through the skin and into the bloodstream, with the use of a patch.